Vesicant Extravasation Part II: Evidence-Based Management and Continuing Controversies

Wickham, Rita; Engelking, Constance; Sauerland, Carmel; Corbi, Dominick

doi:10.1188/06/onf.1143-1150

Cited by 45 publications

(39 citation statements)

References 34 publications

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“…It was observed that, in spite of the protocol defined by the institution, the registrations vary regarding application with the occurrence of extravasation of the same drug, as shown below. an extravasation occurs or is suspected, the infusion is stopped and the affected area should be inspected and the treatment given with the correct antidote to the drug (3)(4)6) .…”

Section: Resultsmentioning

confidence: 99%

Dermatological Toxicity in Women With Breast Cancer Undergoing Chemotherapy Treatment

Gozzo

Panobianco

Clapis

et al. 2010

Rev. Latino-Am. Enfermagem

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Dermatological Toxicity in Women With Breast Cancer Undergoing Chemotherapy TreatmentThis study aimed to analyze the occurrence of skin toxicity caused by drugs used in the protocol of neoadjuvant and adjuvant chemotherapy among women with breast cancer.Patient records of 72 women who were subject to this therapy between 2003 and 2006 were assessed. Of the 558 cycles of chemotherapy, 152 adverse events were registered.There were 37 registrations of dermatological toxicity, of those, 20 were extravasations that affected 17 women. Nine reports of hardened local injury, local fibrosis, pain, and hyperemia were registered during neoadjuvancy. In adjuvancy, among the 11 extravasations registered there were reports of hardened local injury, fibrosis and local pain. Lack of follow-up records for both periods was observed. Registration of the events and reports by the nursing team are essential to monitor the sites of venous puncture during the chemotherapy treatment, besides measuring and making a photographic record of the site.

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Section: Resultsmentioning

confidence: 99%

Dermatological Toxicity in Women With Breast Cancer Undergoing Chemotherapy Treatment

Gozzo

Panobianco

Clapis

et al. 2010

Rev. Latino-Am. Enfermagem

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“…The use of topically administered drugs in the treatment of extravasations is controversial [9,11]. Various "antidotes" (including glucocorticoids, antihistamines, sodium bicarbonate, heparin, and lidocaine) have been injected or topically applied to sites of chemotherapeutic extravasation injuries and have been found to be ineffective in treating such injuries [15]. The use of subcutaneously administered hyaluronidase has been previously advocated for the extravasation of parenteral nutrition [7].…”

Section: Discussionmentioning

confidence: 99%

Extravasation of Parenteral Nutrition in the Neck: A Case Report

Davidoss¹,

Ha²

2017

Gen Int Med Clin Innov

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“…Cellulitis and the formation of abscesses are rare events. 47,48 The interval between detecting the condition and adopting the appropriate measures should be as short as possible. The nursing team should be trained in this respect.…”

Section: Drug Extravasationmentioning

confidence: 99%

Reações tegumentares adversas relacionadas aos agentes antineoplásicos: parte II

Criado

Brandt

Moure

et al. 2010

An. Bras. Dermatol.

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Events and reactions involving chemotherapy are common in clinical oncology. Chemotherapeutic agents are widely used in therapy. Side effects range from the common to the rare and may be confused with other mucocutaneous manifestations resulting from the oncological treatment. The objective of this paper was to present data on skin reactions to chemotherapy, particularly those cases in which the dermatologist is requested to issue a report and asked to comment on the safety and viability of readministration of a specific drug. The authors describe aspects associated with these events, presenting a detailed analysis of each one of them. Keywords: Chemotherapy, adjuvant ; Drug therapy; Drug therapy, combination; Skin; Skin abnormalities; Skin pigmentation Resumo:Os eventos e reações envolvendo quimioterapia são frequentes na prática oncológica. Agentes quimioterápicos são uma modalidade de tratamento amplamente utilizada. Efeitos colaterais podem variar de frequência e também ser confundidos com outras manifestações tegumentares do tratamento oncológico. Este artigo objetiva expor as informações sobre reações cutâneas à quimioterapia, em especial, aqueles para os quais o dermatologista é requisitado a emitir parecer e a comentar sobre a segurança e a viabilidade da readministração de uma droga específica. Os autores descrevem os aspectos associados a esses eventos, fazendo uma análise detalhada de cada um deles.

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Vesicant Extravasation Part II: Evidence-Based Management and Continuing Controversies

Abstract: Nurses who administer vesicant agents should understand the nursing and collaborative actions that should be taken to minimize patient morbidity, pain, and disability.

Cited by 45 publications

References 34 publications

Dermatological Toxicity in Women With Breast Cancer Undergoing Chemotherapy Treatment

Dermatological Toxicity in Women With Breast Cancer Undergoing Chemotherapy Treatment

Extravasation of Parenteral Nutrition in the Neck: A Case Report

Reações tegumentares adversas relacionadas aos agentes antineoplásicos: parte II

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