Very Late Recurrence of Takotsubo Syndrome

Abstract

Recurrence of the Takotsubo syndrome is possible, and in the majority of cases it occurs within 4 years. The present report is focused on a case of the Takotsubo syndrome recurrence after 10 years. The patient had been admitted for the first time in 1999 with a diagnosis of "non-q wave acute anterolateral myocardial infarction." Ten years later, she was readmitted for suspected acute myocardial infarction; coronary arteries, however, were normal, and the left ventricular angiogram demonstrated apical ballooning typical for the Takotsubo syndrome. It is worth noting that the clinical presentation and the ECG were the same on both occasions; in addition, both events were triggered by an emotional stress.

Fatores Associados à Recorrência na Síndrome de Takotsubo: Uma Revisão Sistemática

“…Episódios de recorrência foram relatados por cerca de 22 dias 12 até pouco mais de nove anos após o primeiro episódio. 3 Embora exista um relato de recorrência até dez anos após o episódio inicial, 15 casos como esse são extremamente raros. Looi et al 9 observaram que a recidiva foi mais frequente no primeiro ano após o episódio inicial.…”

“…Episodes of recurrence have been reported for about 22 days 12 until slightly more than nine years after the first episode. 3 Although there is a recurrence report up to ten years after the initial episode, 15 cases like this are extremely rare. Looi et al 9 found that recurrence was more frequent in the first year after the initial episode.…”

Very Early Recurrence of Takotsubo Syndrome

“…Recurrence of Takotsubo syndrome usually occurs in 4 years, on very rare occasions, recurrence has been observed after 10 years, and recurrence occurs in 1 year from the first presentation in 3% of patients. Nevertheless, this patient recurs in only 4 days, so, clinical doctors and families should pay close attention to the patients mood in long time, and avoid mind stimulation, thus, prevent the recurrence of Takotsubo syndrome.…”

Takotsubo Syndrome in Patient with Severe Mitral and Aortic Regurgitation

“…[ 1 2 ] Data on recurrence of Takotsubo syndrome are limited: 5-year recurrence rates of 5%–22% have been reported, with the second episode occurring 3 months to 10 years after the first episode and also were reported recurrence of Takotsubo syndrome with a different anatomical variant. [ 2 3 4 ] In our case, the patient with Takotsubo cardiomyopathy and heart failure due to degenerative mitral and aortic regurgitation underwent the valve replacement surgery with early recurrence of left ventricular systolic dysfunction. Thus, Takotsubo cardiomyopathy may be considered as a risk factor of the postoperative left ventricular dysfunction triggered by surgical/anesthetic procedure.…”