Very High Prevalence of Frozen Shoulder in Patients With Type 1 Diabetes of ≥45 Years' Duration: The Dialong Shoulder Study

Juel, Niels Gunnar; Brox, Jens Ivar; Brunborg, Cathrine; Holte, Kari Anne; Berg, Tore Julsrud

doi:10.1016/j.apmr.2017.01.020

Cited by 42 publications

(49 citation statements)

References 99 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In patients with T1D in Sardinia, adhesive capsulitis was diagnosed in 35.1%. In another study of T1D with a long duration (>45 years), 59% of the patients had frozen shoulder 92 . The prevalence of adhesive capsulitis in the large T1D cohort described in Larkin et al was 31%.…”

Section: Prevalence Of Self-reported Ueismentioning

confidence: 95%

Upper extremity impairments in type 1 diabetes in comparison to matched controls without diabetes : associations to the IGF-system, metabolic factors, disability and quality of life

Gutefeldt

2020

Linköping University Medical Dissertations

View full text Add to dashboard Cite

Compared with the general population, people with type 1 diabetes (T1D) more often exhibit pathological alterations in musculoskeletal tissue (impairments). Some of these impairments involve the upper extremities, i.e., the shoulders, hands, and fingers. Although present in diabetes, these complications are underdiagnosed and not actively searched for during routine clinical examinations. Furthermore, much is still unclear about these impairments, specifically regarding their etiology, risk factors, and consequences on daily life activities and quality of life. The growth hormone (GH)/insulinlike growth factor (IGF)-system is known to be affected in diabetes, but whether this is involved in upper extremity impairments (UEIs) is unclear. The aim of this thesis was to describe the prevalence of UEIs in patients with diabetes compared with controls. Furthermore, we aimed to search for risk factors of UEIs, and elucidate the impact of UEIs on daily life activities and health-related quality of life (HRQOL). We used two cohorts; the LedIG cohort (papers I-III), a large population-based study in which all patients with a long duration of T1D (>20 years), aged <67 years, living in the southeast region of Sweden were invited to participate, as well as matched controls without diabetes. This study was based on questionnaires as well as blood samples from the participants. The last paper (IV) included a smaller cohort (n=69) of patients with T1D, who both completed a questionnaire and were the subjects of a clinical examination. Paper I: The UEIs were common in diabetes, with a prevalence of up to 48%. Hand paresthesia was the most common impairment, followed by shoulder pain and stiffness. The prevalence of UEIs was 2-4 times higher in patients than in controls and was associated with more activity limitations. Risk factors were heterogeneous for the different UEIs and included female sex, increasing age, longer duration of diabetes, and poor glycemic control. Paper II: The GH-IGF-axis is important for the growth and function of musculoskeletal tissues. We examined differences in the IGF system between patients with T1D on subcutaneous insulin treatment and controls. We found lower levels of IGF-I and insulinlike growth factor-binding protein (IGFBP)-3 and higher levels of GH and IGFBP-1 in patients with T1D than in controls. The largest difference was found in IGFBP-1, and this probably reflected insulin deficiency. The IGF-I levels were increased with increasing insulin doses. However, even at very high insulin doses (>1 U/kg) the IGF-I Z-score was subnormal, indicating that IGF-I cannot be normalized by subcutaneous insulin treatment. Residual endogenous insulin secretion counteracted these alterations. SF-36 Short Form Health Survey T1D Type 1 diabetes UEI(s) Upper extremity impairment(s) Insulin and its impact on the IGF system Under normal physiological conditions, insulin produced by the pancreas reaches the liver directly through the portal vein, thereby exposing the liver to much higher concentrations of insulin ...

show abstract

Section: Prevalence Of Self-reported Ueismentioning

confidence: 95%

Upper extremity impairments in type 1 diabetes in comparison to matched controls without diabetes : associations to the IGF-system, metabolic factors, disability and quality of life

Gutefeldt

2020

Linköping University Medical Dissertations

View full text Add to dashboard Cite

show abstract

“…The association between diabetes and AC was first recognized by Bridgman (1972) who found that 10.8% of diabetic patients had AC as compared to 2.3% for nondiabetic patients [8]. Subsequent studies have supported this association and reported a prevalence of 10-76% in type 1 and 7-30% in type 2 diabetes as compared to 0-10% in the general population [9][10][11][12]. Adhesive capsulitis was also reported to be associated with age in both types of diabetes and with the duration in type 1 diabetes [9][10][11]13].…”

Section: Introductionmentioning

confidence: 97%

“…Subsequent studies have supported this association and reported a prevalence of 10-76% in type 1 and 7-30% in type 2 diabetes as compared to 0-10% in the general population [9][10][11][12]. Adhesive capsulitis was also reported to be associated with age in both types of diabetes and with the duration in type 1 diabetes [9][10][11]13]. The pathophysiology that predisposes diabetics for the development of AC is not well understood.…”

Section: Introductionmentioning

confidence: 99%

“…Although some of the non-surgical interventions have been shown to be effective in managing AC, recovery is slow and often incomplete, especially for people with diabetes [22]. Patients with diabetes often develop long-lasting shoulder stiffness, higher shoulder pain, functional disability and reduced ROM than patients without diabetes [10,11,23,24]. Furthermore, higher shoulder pain and disability were associated with poor glycemic control and diabetic complications [25].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Physiotherapy Program for Managing Adhesive Capsulitis in Patients with Diabetes: A Protocol for a Pilot Randomized Trial

MacDermid¹,

Faber²,

Furtado³

et al. 2020

GGR

View full text Add to dashboard Cite

Background: Adhesive capsulitis (AC) occurs five times more often in people with diabetes and leads to prolonged disability. Exercises and joint mobilization are usually used to manage AC. However, the recovery is slow and often incomplete. Aerobic exercises improve hyperglycemia and insulin sensitivity. Currently, no research has formally assessed the benefits of incorporating an aerobic training program into the treatment plan of AC in patients with diabetes. This single blind pilot randomized trial will compare the preliminary effect of a regular physiotherapy program (PT), to a regular PT program combined with a progressive walking program (PT+) in patients with and without diabetes who have AC. Methods: Patients (n= 40) will be recruited from St. Joseph's HealthCare Centre and associated primary care practices. Patients will be randomly assigned into either the regular PT program or regular PT combined with a progressive walking program. Patients will be referred to physical therapy facilities and the intervention will be chosen by the treating physical therapist. In the PT+ group, patients will be asked to perform free walking at their own pace for 30-45 minutes, five days per week, for six consecutive weeks. The primary outcome will be testing the functional performance of the shoulder using the Functional Impairment Test- Hand and Neck/ Shoulder/Arm (FIT-HaNSA) test. Secondary outcomes will include shoulder pain and function using the Shoulder Pain and Disability Index (SPADI) questionnaire; shoulder range of motion in flexion, abduction, and external rotation; muscles strength of shoulder flexors and abductors; and physical activity level using an accelerometer and the Rapid Assessment of Physical Activity (RAPA) questionnaire. The primary outcome will be evaluated at baseline and after six weeks. Secondary outcomes will be evaluated at baseline, and after three, six and 12 weeks from enrolment. Discussion: The novel approach taken in this pilot trial will establish the preliminary effect of a regular PT program combined with a progressive walking program and will evaluate a study design prior to the performance of a full-scale research project that may lead to better outcomes for managing adhesive capsulitis in people with diabetes.

show abstract

“…Examples of latter are frozen shoulder (FS) and hemiplegic shoulder pain (HSP). While the prevalence of FS among the general population is 2%–4%, it affects up to 59% of patients with long‐term diabetes mellitus . HSP is a frequent unfortunate stroke sequel with the reported incidence of shoulder pain of 47% at 12 months .…”

Section: Introductionmentioning

confidence: 99%

Peripheral Nerve Stimulation for Chronic Shoulder Pain: A Proof of Concept Anatomy Study

Agur

2018

Neuromodulation: Technology at the Neural Interface

View full text Add to dashboard Cite

Very High Prevalence of Frozen Shoulder in Patients With Type 1 Diabetes of ≥45 Years' Duration: The Dialong Shoulder Study

Abstract: The point prevalence of frozen shoulder in patients with long-lasting type 1 diabetes was 59%, and the lifetime prevalence was 76%. The diabetes group had more shoulder disability than diabetes-free subjects. The historical HbA level was associated with increased shoulder disability.

Cited by 42 publications

References 99 publications

Upper extremity impairments in type 1 diabetes in comparison to matched controls without diabetes : associations to the IGF-system, metabolic factors, disability and quality of life

Upper extremity impairments in type 1 diabetes in comparison to matched controls without diabetes : associations to the IGF-system, metabolic factors, disability and quality of life

Physiotherapy Program for Managing Adhesive Capsulitis in Patients with Diabetes: A Protocol for a Pilot Randomized Trial

Peripheral Nerve Stimulation for Chronic Shoulder Pain: A Proof of Concept Anatomy Study

Contact Info

Product

Resources

About