Very-high-power short-duration ablation for treatment of premature ventricular contractions – The FAST-AND-FURIOUS PVC study

Heeger, Christian‐Hendrik; Popescu, Sorin; Kirstein, Bettina; Hatahet, Sascha; Traub, Anna; Phan, Huong-Lan; Feher, Marcel; D́Ambrosio, Gabriele; Kazemi, Ahmad; Schlüter, Michael; Vogler, Julia; Eitel, Charlotte; Kück, Karl‐Heinz; Tilz, Roland Richard

doi:10.1016/j.ijcha.2022.101042

Cited by 9 publications

(15 citation statements)

References 23 publications

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“…The median RF delivery time was massively reduced utilizing vHPSD ( p < .0001). No difference was observed regarding procedure duration ( p = .489), follow‐up ( p = .712) and severe adverse events (4%, study group, 8%, control group, p = .551) 34 …”

Section: Ablation Of Premature Ventricular Contractions Utilizing Qmode+mentioning

confidence: 94%

“…Only one case report and one study for catheter ablation of PVC utilizing the QDOT MICRO™ Catheter have been published in humans up to date. 34,38 In the initial case report a patient with frequent monomorphic PVC and severe adverse events (4%, study group, 8%, control group, p = .551). 34 Although the FAST and FURIOUS PVC study was a single center nonrandomized study it demonstrated the feasibility and safety of the QDOT MICRO™ Catheter for treatment of OVC originated from the RVOT and LVOT.…”

Section: Ablation Of Premature Ventricular Contractions Utilizing Qmode+mentioning

confidence: 99%

“…34,38 In the initial case report a patient with frequent monomorphic PVC and severe adverse events (4%, study group, 8%, control group, p = .551). 34 Although the FAST and FURIOUS PVC study was a single center nonrandomized study it demonstrated the feasibility and safety of the QDOT MICRO™ Catheter for treatment of OVC originated from the RVOT and LVOT. In the thin walled RVOT, the success rate of vHPSD was 92%, while it was 42% for LVOT case.…”

Section: Ablation Of Premature Ventricular Contractions Utilizing Qmode+mentioning

confidence: 99%

“…Although vHPSD concepts have been evaluated for atrial procedures, data for ablation within the ventricles is very limited. Only one case report and one study for catheter ablation of PVC utilizing the QDOT MICRO™ Catheter have been published in humans up to date 34,38 …”

Section: Ablation Of Premature Ventricular Contractions Utilizing Qmode+mentioning

confidence: 99%

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Very high‐power short‐duration catheter ablation for treatment of cardiac arrhythmias: Insights from the FAST and FURIOUS study series

Heeger,

Kuck,

Tilz

2023

Cardiovasc electrophysiol

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The QDOT MICRO™ Catheter is a novel open‐irrigated contact force‐sensing radiofrequency ablation catheter. It offers very high‐power short‐duration (vHPSD) ablation with 90 W for 4 s to improve safety and efficacy of catheter ablation procedures. Although the QDOT MICRO™ Catheter was mainly designed for pulmonary vein isolation (PVI) its versatility to treat atrial fibrillation (AF) and other types of arrhythmias was recently evaluated by the FAST and FURIOUS study series and other studies and will be presented in this article. Available study and registry data as well as case reports concerning utilization of the QDOT MICRO™ Catheter for the treatment of cardiac arrhythmias including AF, focal and macroreentry atrial tachycardia, typical atrial flutter by cavotricuspid isthmus block, premature ventricular contractions, and accessory pathways were reviewed and summarized. In summary, the QDOT MICRO™ Catheter showed safety and efficacy for PVI and is able to treat also other types of arrhythmias as is was recently evaluated by case reports and the FAST and FURIOUS studies.

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Section: Ablation Of Premature Ventricular Contractions Utilizing Qmode+mentioning

confidence: 94%

Section: Ablation Of Premature Ventricular Contractions Utilizing Qmode+mentioning

confidence: 99%

Section: Ablation Of Premature Ventricular Contractions Utilizing Qmode+mentioning

confidence: 99%

Section: Ablation Of Premature Ventricular Contractions Utilizing Qmode+mentioning

confidence: 99%

See 2 more Smart Citations

Very high‐power short‐duration catheter ablation for treatment of cardiac arrhythmias: Insights from the FAST and FURIOUS study series

Heeger,

Kuck,

Tilz

2023

Cardiovasc electrophysiol

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“…In the current issue of this Journal, Heeger et al describe their experience in using vHPSD applied by the temperature-controlled and irrigated QDOT MICRO® (Biosense Webster) catheter to treat patient with idiopathic premature ventricular contractions (PVCs) [6] . PVCs arising from the outflow tract are the most common subtype of idiopathic ventricular arrhythmia and more than 70–80% of those originate from the right ventricular outflow tract (RVOT) and are often located in the distal septal and anterior surface of the RVOT, while a free wall focus has only been reported in 20–30% of patients undergoing radiofrequency ablation [7] , [8] .…”

mentioning

confidence: 99%

Very high-power short-duration ablation for treatment of premature ventricular contractions: Truth or Dare?

Chaldoupi

Luermans

Linz

2022

IJC Heart & Vasculature

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Where is the gap after a 90 W/4 s very‐high‐power short‐duration ablation of atrial fibrillation?: Association with the left atrial‐pulmonary vein voltage and wall thickness

Hirata,

Nagashima,

Watanabe

et al. 2024

Journal of Arrhythmia

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BackgroundAlthough pulmonary vein isolation (PVI) for atrial fibrillation (AF) utilizing radiofrequency (RF) applications with a very high‐power and short‐duration (vHPSD) has shortened the procedure time, the determinants of pulmonary vein (PV) gaps in the first‐pass PVI and acute PV reconnections are unclear.MethodsAn extensive encircling PVI was performed with the QDOT MICRO catheter with a vHPSD (90 W–4 s) in 30 patients with AF (19 men, 64 ± 10 years). The association of the PV gap sites (first‐pass PVI failure, acute PV reconnections [spontaneous reconnections or dormant conduction provoked by adenosine triphosphate] or both) with the left atrial (LA) wall thickness and LA bipolar voltage on the PVI line and ablation‐related parameters were assessed.ResultsPV gaps were observed in 29 (6%) of 480 segments (16 segments per patient) in 17 patients (56%). The PV gaps were associated with the LA wall thickness, bipolar voltage, and the number of RF points (LA wall thickness, 2.5 ± 0.5 vs. 1.9 ± 0.4 mm, p < .001; bipolar voltage, 2.59 ± 1.62 vs. 1.34 ± 1.14 mV, p < .001; RF points, 6 ± 2 vs. 4 ± 2, p = .008) but were not with the other ablation‐related parameters. Receiver operating characteristic curves yielded that an LA wall thickness ≥2.3 mm and bipolar voltage ≥2.40 mV were determinants of PV gaps with an area under the curve of 0.82 and 0.73, respectively.ConclusionsThe LA voltage and wall thickness on the PV‐encircling ablation line were highly associated with PV gaps using the 90 W/4 s‐vHPSD ablation.

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Very-high-power short-duration ablation for treatment of premature ventricular contractions – The FAST-AND-FURIOUS PVC study

Cited by 9 publications

References 23 publications

Very high‐power short‐duration catheter ablation for treatment of cardiac arrhythmias: Insights from the FAST and FURIOUS study series

Very high‐power short‐duration catheter ablation for treatment of cardiac arrhythmias: Insights from the FAST and FURIOUS study series

Very high-power short-duration ablation for treatment of premature ventricular contractions: Truth or Dare?

Where is the gap after a 90 W/4 s very‐high‐power short‐duration ablation of atrial fibrillation?: Association with the left atrial‐pulmonary vein voltage and wall thickness

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