Very Acute and Aggressive Form of Marjolin???s Ulcer Caused by Single Blunt Trauma to the Burned Area

Copçu, Eray; Sivrioğlu, Nazan; Baytekin, Caghan; Koç, Banu; Er, Sule

doi:10.1097/01.bcr.0000176967.74674.64

Cited by 9 publications

(6 citation statements)

References 5 publications

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“…In 1976, Fitzgerald stated that lymph node excision should be done only if there is no decrease in the size of the lymph node 3 months after excision of the malignant ulcer. 22 Bostwick and colleagues recommended elective regional lymph node dissection 2 to 4 weeks after local excision. 23 No consensus has been reached yet.…”

Section: Discussionmentioning

confidence: 99%

Marjolin Ulcer: Clinical Experience with 34 Patients over 15 Years

et al. 2013

J Cutan Med Surg

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Background: Malignancies that arise from scars are referred to as Marjolin ulcers. The association between chronic ulcers and squamous cell carcinomas is well established. There are many case reports in the literature regarding Marjolin ulcer; however, randomized controlled clinical series that describe a thorough evaluation of these patients are rarely encountered.Objective: We present our clinic's 15 years of experience with 34 Marjolin ulcer patients and their treatment modalities.Methods: A retrospective analysis of 302 squamous cell carcinoma patients who were treated in the plastic surgery department between 1997 and 2011 was performed. Thirty-four (10.3%) histopathologically confirmed Marjolin ulcer patients were further analyzed.Results: Although burn scars represented 77% of the patients in the present study, unstable scars that formed following traffic accidents and fistula tracts are also among the commonly encountered etiologies. Based on our observations, squamous cell carcinoma, in addition to malignant melanoma and verrucous carcinoma, is frequently observed in cases of Marjolin ulcers. Conclusion:If the goal is to eradicate this clinical entity, all of the chronic ulcers that fail to heal require biopsies at regular intervals. Large excisional margins, lymphadenectomies in cases of palpable lymph nodes, and a well-defined oncology protocol are all essential in treating Marjolin ulcer. Contexte: Les tumeurs malignes qui se dé veloppent aux dé pens des cicatrices sont appelées ulcè res de Marjolin. L'association entre les ulcè res chroniques et les carcinomes squameux est bien connue. La documentation contient de nombreux exposé s de cas d'ulcère de Marjolin, mais très peu de sé ries de cas cliniques, comparatives et alé atoires, faisant état d'une é valuation complè te des patients touchés. Objectif: Il sera question de notre expé rience accumulé e pendant 15 ans, dans notre é tablissement, chez 34 patients atteints d'un ulcè re de Marjolin ainsi que des diffé rentes formes de traitement. Mé thode: Il s'agit d'une analyse ré trospective de 302 cas de carcinome squameux, traité s au service de chirurgie plastique, de 1997 à 2011; 34 (10.3%) d'entre eux ont fait l'objet d'une analyse approfondie, l'examen histopathologique ayant ré vé lé la pré sence d'un ulcè re de Marjolin.Ré sultats: Les cicatrices de brû lure constituaient 77% des cas retenus dans l'é tude, mais les cicatrices instables, qui se forment à la suite d'accidents de la route, et les trajets fistuleux figurent aussi parmi les causes courantes de cette affection. D'aprè s les notes recueillies, le carcinome squameux, outre le mé lanome malin et le carcinome verruqueux, s'observe souvent dans les cas d'ulcère de Marjolin.Conclusions: Si le but est d'é liminer cette entité morbide, les biopsies à intervalles ré guliers s'imposent dans tous les cas d'ulcè re chronique qui ne cicatrise pas normalement. La ré alisation de bonnes marges saines, les lymphadé nectomies dans les cas de noeuds lymphoïdes palpables et l'é tablissement d'un protoco...

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Section: Discussionmentioning

confidence: 99%

Marjolin Ulcer: Clinical Experience with 34 Patients over 15 Years

et al. 2013

J Cutan Med Surg

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“…Computed tomography and MRI can be very useful tools in the evaluation of Marjolin's ulcer; MRI is a safe and rapid method, especially in tumors that invade surrounding tissue. 25 In addition, it is an effective means of excluding a metastatic process.…”

Section: Discussionmentioning

confidence: 99%

Marjolin’s Ulcer of the Hallux

Pavlovic

Surowiec

Braniecki

2013

J Am Podiatr Med Assoc

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We report the case of a 51-year-old woman with malignant degeneration of a right hallux nail bed ulcer of 20 years' duration. Histologic examination confirmed the diagnostic features of Marjolin's ulcer, a well-defined but uncommon malignant ulcer that occurs in chronic wounds and cutaneous scars. In this report, we describe the clinical and histopathologic features and the differential diagnosis of this unusual lesion.

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“…Moreover, it is an effective means of excluding a metastatic process. MRI may be performed as a safe and rapid method, especially in tumours that aggressively invade surrounding tissue (33). In addition, lymph nodes should be carefully examined in all patients.…”

Section: Discussionmentioning

confidence: 99%

Marjolin ulcer: an overlooked entity

Pavlovic

Wiley

Guzman

et al. 2011

International Wound Journal

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Marjolin ulcer is a well-defined, but uncommon malignant ulcer that occurs in chronic wounds and cutaneous scars. Jean-Nicolas Marjolin was credited with describing this phenomenon in 1828. This entity is frequently overlooked and therefore inadequately treated leading to a poor prognosis. The malignant transformation of an ulcer is most commonly associated with burn scars, but has been reported in many other types of chronic, non healing wounds such as traumatic wounds, venous stasis and chronic pressure ulcers, fistulas, lacerations and leprosy ulcers. Development of malignancy tends to be slow with an average time of approximately 25 years. Various theories concerning pathogenesis of Marjolin ulcer have been proposed. Well-differentiated squamous cell carcinoma (SCC) is the most common histological type of Marjolin ulcer. Biopsy with histopathologic interpretation remains the gold standard for the diagnosis, with radical surgical excision being the treatment of choice. A high index of suspicion should be held by any health care provider when evaluating a chronic, non healing wound. This is a case report of a Marjolin ulcer arising on the left buttock of a patient with a long-standing history of a traumatic wound.

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Very Acute and Aggressive Form of Marjolin???s Ulcer Caused by Single Blunt Trauma to the Burned Area

Cited by 9 publications

References 5 publications

Marjolin Ulcer: Clinical Experience with 34 Patients over 15 Years

Marjolin Ulcer: Clinical Experience with 34 Patients over 15 Years

Marjolin’s Ulcer of the Hallux

Marjolin ulcer: an overlooked entity

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