Vertical transmission of Toxoplasma gondii in naturally infected ewes in the semiarid region of Brazil

Costa, Flávia Teresa Ribeiro da; Nogueira, Diogo Pupo; Oliveira, Maria A.G.; Silva, Samara S.; Silva, Rômulo F.; Sarmento, Wlysse Ferreira; Azevêdo, Sérgio Santos de; Gennari, Solange Maria; Pena, Hilda Fátima Jesus; Brasil, Arthur Willian de Lima; Vilela, Vinícius Longo Ribeiro; Feitosa, Thaís Ferreira

doi:10.1016/j.cimid.2020.101595

Cited by 8 publications

(4 citation statements)

References 19 publications

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“…The results obtained for T. gondii and N. caninum was within the positivity average of other studies carried out in the country ( Silva et al, 2012 ; Romanelli et al, 2020 ; Costa et al, 2021 ). In addition to its importance for public health, T. gondii is one of the main abortifacient agents in small ruminants, and human infection can result in abortion or neurological infection in immunosuppressed individuals ( Stelzer et al, 2019 ).…”

supporting

confidence: 87%

Occurrence of IgG antibodies against Toxoplasma gondii, Neospora caninum, and Leptospira spp. in goats and sheep from an indigenous village in Pernambuco, Brazil

Galvão

Oliveira

Cavalcanti

et al. 2023

Rev. Bras. Parasitol. Vet.

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This study aimed to determine the occurrence of anti-Toxoplasma gondii, Neospora caninum, and Leptospira spp. antibodies in sheep and goats raised in villages of the Xukuru do Ororubá indigenous community, Pernambuco, Brazil. A total of 180 serum samples from sheep and 108 serum samples from goats of both sexes and different ages were analyzed. For antibody research, indirect immunofluorescence antibody test (IFAT) were used for the protozoa T. gondii and N. caninum, and microscopic agglutination test (MAT) for Leptospira spp., with a cutoff titer of 1:64, 1:50 and 1:100, respectively. The frequency of anti-T. gondii antibodies was 16.6% (30/180) for sheep and 11.1% (12/108) for goats. The frequency of anti-N. caninum antibodies was 10.55% (19/180) for sheep, and 20.37% (22/108) for goats, while for Leptospira spp., 2.2% (4/180) of sheep and 1.85% (2/108) of goats reacted positively. The results obtained in this study are unprecedented in indigenous communities in the country and serve as an alert for monitoring goats and sheep from the Xukuru do Ororubá indigenous village regarding the occurrence and productive impact of infections by T. gondii, N. caninum, and Leptospira spp., in addition to the occurrence of the zoonosis toxoplasmosis and leptospirosis in the indigenous community.

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supporting

confidence: 87%

Occurrence of IgG antibodies against Toxoplasma gondii, Neospora caninum, and Leptospira spp. in goats and sheep from an indigenous village in Pernambuco, Brazil

Galvão

Oliveira

Cavalcanti

et al. 2023

Rev. Bras. Parasitol. Vet.

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“…Sheep can be infected with T. gondii via ingestion of feed or water contaminated with oocysts that have been shed by a feline definitive host [ 4 ]. Vertical transmission after pregnancy-induced recrudescence of persistent infections has also been reported [ 5 , 6 ]. Reproductive disease is generally observed only following a primary infection in a naïve pregnant ewe, and T. gondii infection usually confers long-lasting protective immunity [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Toxoplasma gondii is not an important contributor to poor reproductive performance of primiparous ewes from southern Australia: a prospective cohort study

et al. 2022

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Background Toxoplasma gondii causes reproductive losses in sheep worldwide, including Australia. The reproductive performance of primiparous ewes is typically lower than for mature, multiparous ewes, and younger ewes are more likely to be immunologically naïve and therefore more susceptible to reproductive disease if T. gondii infection occurs during pregnancy. The aim of this study was to assess the impact of infection with T. gondii on the reproductive performance of primiparous ewes in southern Australia using a prospective cohort study. This will inform the need for targeted control strategies for T. gondii in Australian sheep. Results Toxoplasma gondii seropositivity using indirect ELISA was detected at 16/28 farms located across southern Australia. Apparent seropositivity to T. gondii was lower in primiparous ewes (1.1, 95% confidence interval (CI) 0.6, 1.8) compared to mature, multiparous ewes (8.1, 95% CI 6.0, 10.5; P < 0.001). Toxoplasma gondii seroconversion during the gestation and lambing period was confirmed for 11/1097 (1.0, 95% CI 0.5, 1.7) of pregnant primiparous ewes that failed to raise a lamb, and 1/161 (0.6, 95% CI 0.1, 2.9) primiparous ewes with confirmed mid-pregnancy abortion. Conclusions Low frequency of detection of T. gondii seroconversion during gestation and low frequency of seropositivity to T. gondii suggests that toxoplasmosis was not an important contributor to reproductive losses in primiparous ewes on farms located over a wide geographical area in southern Australia.

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“…Na América do Sul, as infecções pelo protozoário variam entre 3 a 54% dos abortos ovinos (STELZER et al, 2019). Na região Semiárida da Paraíba, foi avaliado e observado a presença de anticorpos IgG anti-T. gondii em fêmeas ovinas do nascimento até os 12 meses, no qual 44,3% das fêmeas possuiam uma alta probabilidade de ocorrência de desordens reprodutivas causadas pelo parasito (VALENCIO et al, 2020;COSTA et al, 2021).…”

Section: A Toxoplasmose Ovina E Suas Repercussões Na Reproduçãounclassified

Toxoplasmose Ovina: Revisão de Literatura

Lima

Melo²

2022

UNICIÊNCIAS

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A ovinocultura é desenvolvida em diversas regiões do país e do mundo, formada por animais com capacidade de adaptação a condições ambientais adversas, e neste cenário, o Brasil se destaca por ser considerado o primeiro produtor de ovinos do Continente Americano, com um rebanho de aproximadamente 18 milhões de cabeças. Nesse contexto, diversas enfermidades infecciosas têm provocado grandes prejuízos, incluindo aquela causada pelo protozoário Toxoplasma gondii, que resulta em problemas reprodutivos e perdas econômicas na ovinocultura. O T. gondii é o agente etiológico da toxoplasmose, uma importante zoonose, com distribuição cosmopolita e de grande interesse em saúde pública. Trata-se de um agente que pode provocar sérios danos aos fetos, pela transmissão vertical tanto em humanos quanto nos animais podendo causar abortamento ou infecção congênita em seus hospedeiros intermediários, tendo os felídeos como os únicos hospedeiros definitivos. Este artigo foi elaborado por meio de pesquisa bibliográfica, com o objetivo de abordar acerca da toxoplasmose ovina. Diversos trabalhos têm demonstrado a detecção do parasito em carnes destinadas ao abate, sendo muito relevante em âmbito de saúde pública, pois é uma fonte de infecção para os humanos caso não seja realizado o cozimento destes alimentos de maneira eficiente. Por isso, é essencial que sejam estabelecidas medidas sanitárias nas criações de ovinos como forma de prevenir a propagação da doença. Palavras-chave: Protozoário. Ovinocultura. Abortamento. Abstract Sheep farming is developed in several regions of the country and the world, made up of animals with the ability to adapt to adverse environmental conditions, and in this scenario, Brazil stands out for being considered the first sheep producer on the American continent, with a herd of approximately 18 million heads. In this context, several infectious diseases have caused great damage, including that caused by the protozoan Toxoplasma gondii, which results in reproductive problems and significant economic losses in sheep farming. T. gondii is the etiologic agent of toxoplasmosis, an important zoonosis, with cosmopolitan distribution and great interest in public health. It is an agent that can cause serious damage to fetuses, due to vertical transmission in both humans and animals, causing abortion or congenital infection in their intermediate hosts, and the felids are the only definitive hosts. This article was elaborated through bibliographical research, with the objective of approaching the one about sheep toxoplasmosis. Several studies have demonstrated the parasite detection in meat intended for slaughter, which is very relevant in terms of public health, as it is a source of infection for humans if these foods are not cooked efficiently. Therefore, it is essential to establish sanitary measures in sheep farming as a way to prevent the spread of the disease. Keywords: Protozoa. Sheep farming. Abortion.

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Vertical transmission of Toxoplasma gondii in naturally infected ewes in the semiarid region of Brazil

Cited by 8 publications

References 19 publications

Occurrence of IgG antibodies against Toxoplasma gondii, Neospora caninum, and Leptospira spp. in goats and sheep from an indigenous village in Pernambuco, Brazil

Occurrence of IgG antibodies against Toxoplasma gondii, Neospora caninum, and Leptospira spp. in goats and sheep from an indigenous village in Pernambuco, Brazil

Toxoplasma gondii is not an important contributor to poor reproductive performance of primiparous ewes from southern Australia: a prospective cohort study

Toxoplasmose Ovina: Revisão de Literatura

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