Vertical distraction osteogenesis of frontal segment and platelet-rich plasma in the edentulous mandible

Abstract

In patients with atrophy of the alveolar ridge of classes V and VI according to Cawood and Howell, the distraction osteogenesis (DO) is the only possibility of reconstruction connected with subsequent dental implants. This method was introduced by Ilizarov (1989), a Russian doctor. In the past few years, the distraction devices have undergone several changes and technical improvements. The usage of platelet-rich plasma (PRP) and autologous bone-platelet gel (ABPG) serving as the source of growth factors is considered a signifi cant progress. The increase in the level of growth factors leads to new bone formation and in soft tissues enhances the healing around the bone and bone wound, lowers the risk of postoperative complications such as pain, swelling and bleeding as well as enables fast placement of implants (Ref. 19).

Platelet-Rich Plasma in Bone Regeneration: Engineering the Delivery for Improved Clinical Efficacy

“…Clinically, the majority of autologous platelet gel and bone graft experiments focus on oral and maxillofacial bone regenerations with much success, short- and long-term [64–66]. Not only have autologous bone-platelet gels enhanced bone formation, but they are also associated with enhanced healing of soft tissues around the bone and bone wound, most likely as a result of the increased level of localized growth factors [67]. While not a randomized trial, another clinical study involving 14 patients was able to quantify the advantage of using autologous bone with platelet gels compared to autograft alone.…”