Vertebroplasty and Kyphoplasty for Metastatic Spinal Lesions: A Systematic Review

Sadeghi, Mohsen Mir Mohammad; Janani, Leila; Aarabi, Shahram; Shokraneh, Farhad; Rahimi‐Movaghar, Vafa

doi:10.1055/s-0036-1582901

Cited by 6 publications

(6 citation statements)

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“…The first was described initially for treatment for vertebral angiomas (5), since then it has been established for the treatment of malignant vertebral condition as well as benign (6). This procedure can be realized under imaging guidance, and consist in insert a gross needle to the vertebral body affected via transpedicular for injection of methyl methacrylate (7).…”

Section: Discussionmentioning

confidence: 99%

A Colombian experience involving SpineJack®, a consecutive series of patients experiencing spinal fractures, percutaneous approach and anatomical restoration 2016–2017

Montoya¹,

Torres²,

Ferrer³

et al. 2018

J Spine Surg

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Background: Spinal fractures are becoming more frequent and should be handled as a severe and endemic pathology that requires timely diagnosis and adequate treatment. The classification of the AOSpine is currently the classification used for this type of fractures, not only for its approach, but to predict surgical management.Methods: These patients had spinal fracture reduction procedures done through percutaneous way with expander endovertebral implants, and intraosseous fixation using SpineJack ® intravertebral implants plus Cohesion ® cement. Within the follow-up scheme, subsequent measurements were taken after a week, a month after surgery, 3 months after the procedure and after 6 months of follow-up. STATA ® (Statistical Analysis System, version 12.1, SAS Institute Inc., Cary, NC, USA) was used for all analyzes. The Wilcoxon or Student's t-test was used for comparisons in pairs depending on the normality of the distribution.Results: A clinical follow-up is performed to 20 consecutive patients experiencing spinal compression fractures (SCF) who received percutaneous treatment involving SpineJack ® and Cohesion ® cement, resulting in a statistically significant decrease of both pain and pain-related disability. No complications arose from the procedure.Conclusions: According to the observations, which reflect what is found in the world literature, this is an effective and safe way of handling SCF.

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Section: Discussionmentioning

confidence: 99%

A Colombian experience involving SpineJack®, a consecutive series of patients experiencing spinal fractures, percutaneous approach and anatomical restoration 2016–2017

Montoya¹,

Torres²,

Ferrer³

et al. 2018

J Spine Surg

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“…Percutaneous vertebral augmentation, itself, is used for pain caused by vertebral metastasis, with evidence showing efficacy in pain response when used as a single modality of treatment. [25][26][27] However, since both groups of patients underwent PVA, it is still significant that there was lower risk of progression in those receiving RT in addition to RFA.…”

Section: Discussionmentioning

confidence: 99%

Radiofrequency Ablation and Radiation Therapy Improve Local Control in Spinal Metastases Compared to Radiofrequency Ablation Alone

Prezzano

Prasad

Hermann

et al. 2018

Am J Hosp Palliat Care

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Purpose: The spinal column is the most common location for osseous metastases and is associated with pain and decreased quality of life. This study evaluated combined radiofrequency ablation (RFA) with radiation therapy (RT) compared to RFA alone for improving pain and local control. Methods: This was a single-institution retrospective review of patients who underwent RFA of spinal metastases between 2016 and 2017, with or without RT to the same vertebral level. Pain was measured with visual analog scale at initial presentation and at 3 and 12 weeks of follow-up. Local failure (LF), distant failure, and overall survival (OS) were compared and Kaplan-Meier statistics were calculated. Results: Twenty-six patients with 28 spinal metastases were treated with RFA. Ten patients with 11 metastases were treated with RFA + RT. More patients with lung primaries were treated with RFA alone and more patients with breast primaries were treated with combination RFA+RT. There was no significant difference in pain scores between groups (P = .96). At a median follow-up of 8.2 months, LF was noted in 8 of 17 metastases treated with RFA alone compared to 1 of 11 metastases treated with RFA+RT (P = .049). There was a significant benefit in time to LF favoring RFA+RT (P = .02) and a significant benefit in OS (P = .0045). Conclusion: This study demonstrates a benefit in local control with RFA+RT versus RFA alone. Palliation of pain was effective using both regimens. This study was limited by a nearly unequal distribution of primary tumor histologies between groups. Literature regarding combined treatment of RFA and RT for spinal metastases is scarce and prospective protocols are warranted.

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“…In addition, pedicle screws interfered with the radiation dose distribution of the vertebral body, resulting in insu cient radiation dose near the vertebral segment of spinal metastases [28] . Through the thermal and chemical effects in the process of solidi cation, bone cement can inhibit the invasion of bone metastases [29] .…”

Section: Effect Of Cement Augmented Pedicle Screw On Local Control Ratementioning

confidence: 99%

Efficacy and Safety of Cement Augmented Fenestrated Screws in the Surgery With Posterior Approach for Spinal Metastases  

Wang

Zang

et al. 2020

Preprint

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Objective: To investigate the efficacy and safety of cement augmented fenestrated screws in the posterior approach for spinal metastases.Methods: A total of 52 patients with spinal metastases who underwent surgery with posterior approach separation and internal fixation with pedicle screw in the Department of Orthopaedics of the Fourth Hospital of Hebei Medical University from January 2015 to January 2017 were analyzed retrospectively. There were 28 cases in the cement augmented pedicle screw group and 24 cases in the conventional pedicle screw group. The clinical data, preoperative and postoperative pain, and neurological function between the two groups were compared. After follow-up, every 3 months, the local progression-free survival time of patients in the two groups was recorded to explore the safety of cement augmented pedicle screws in posterior separation of spinal metastases, and to analyze the difference in efficacy between the two groups.Results: There were no significant differences in sex, age, segments of the affected vertebra, Tomita score, Tokuhashi score, spinal instability neoplastic score (SINS), intraoperative blood loss and average postoperative hospital stays between the two groups. The average operation time was 161 ± 21 minutes in the cement augmented pedicle screw group and 135 ± 19 minutes in the conventional pedicle screw group, with a statistically significant difference. A total of 218 screws were implanted in the 28 patients of the cement augmented pedicle screw group, with an average of 1.3 ± 0.4 ml of cement injected into each screw. There was 1 case of cerebrospinal fluid leakage in each of the two groups, and no incision hematoma formation or infection occurred. There was no symptomatic pulmonary cement embolism in the cement augmented pedicle screw group. The preoperative VAS scores were not statistically different between the two groups. However, the VAS scores in the two groups decreased 3 months after surgery, which were 2.93 ± 1.33 and 4.17 ± 1.34, respectively, with statistical significance. The recovery of Frankel grading was found in 84.6% of all patients (44 cases in 52 patients), but there was no significant difference in Frankel grades between the two groups before and 3 months after surgery. During the follow-up period of 6-24 months, there were 10 cases of adjacent segmental metastasis (2 cases in cement augmented pedicle screw group and 8 cases in conventional pedicle screw group) and 8 cases of internal fixation failure (1 case cement augmented pedicle screw group and 7 cases in conventional pedicle screw group). The difference was statistically significant. Compared with the conventional pedicle screw group, the conventional pedicle screw group had a longer survival time of progression-free in the local and adjacent segments, and the difference was statistically significant. Conclusion: The application of cement augmented pedicle screw in surgery of spinal metastases with the posterior approach is safe, and the pain score decreases more obviously 3 months after surgery. It can effectively reduce the adjacent segmental metastasis and failure rate of internal fixation and prolong the local progression-free survival time.

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Vertebroplasty and Kyphoplasty for Metastatic Spinal Lesions: A Systematic Review

Cited by 6 publications

References 0 publications

A Colombian experience involving SpineJack®, a consecutive series of patients experiencing spinal fractures, percutaneous approach and anatomical restoration 2016–2017

A Colombian experience involving SpineJack®, a consecutive series of patients experiencing spinal fractures, percutaneous approach and anatomical restoration 2016–2017

Radiofrequency Ablation and Radiation Therapy Improve Local Control in Spinal Metastases Compared to Radiofrequency Ablation Alone

Efficacy and Safety of Cement Augmented Fenestrated Screws in the Surgery With Posterior Approach for Spinal Metastases

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Vertebroplasty and Kyphoplasty for Metastatic Spinal Lesions: A Systematic Review

Cited by 6 publications

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A Colombian experience involving SpineJack®, a consecutive series of patients experiencing spinal fractures, percutaneous approach and anatomical restoration 2016–2017

A Colombian experience involving SpineJack®, a consecutive series of patients experiencing spinal fractures, percutaneous approach and anatomical restoration 2016–2017

Radiofrequency Ablation and Radiation Therapy Improve Local Control in Spinal Metastases Compared to Radiofrequency Ablation Alone

Efficacy and Safety of Cement Augmented Fenestrated Screws in the Surgery With Posterior Approach for Spinal Metastases&nbsp;&nbsp;

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Efficacy and Safety of Cement Augmented Fenestrated Screws in the Surgery With Posterior Approach for Spinal Metastases