Vertebroplasty and kyphoplasty: complementary techniques for the treatment of painful osteoporotic vertebral compression fractures. A prospective non-randomised study on 154 patients

Lovi, Alessio; Teli, Marco; Ortolina, Alessandro; Costa, Francesco; Fornari, Maurizio; Brayda-Bruno, Marco

doi:10.1007/s00586-009-0986-9

Cited by 60 publications

(68 citation statements)

References 25 publications

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“…6). The results of the five trials [15,22,29,36,39] that provided long-term ODI data were consistent with these short-term outcomes (Fig. 7).…”

Section: Primary Outcomessupporting

confidence: 69%

“…A total of 242 titles and abstracts were preliminarily reviewed, of which 12 studies [11,15,17,22,28,29,33,36,39,41,48,49] eventually satisfied the eligibility criteria ( Fig. 1).…”

Section: Search Resultsmentioning

confidence: 99%

“…1). These studies included one randomized controlled trial [28], three clinical controlled trials [15,36,41], five prospective cohort studies [11,22,29,33,39], three retrospective cohort studies [17,48,49] and no retrospective case series study. In total, 1081 patients and 1332 vertebral bodies were included in the 12 studies.…”

Section: Search Resultsmentioning

confidence: 99%

“…Among the 12 included studies, only 1 RCT [28] had a low risk of bias, and the remaining 11 non-RCT [11,15,17,22,29,33,36,39,41,48,49] studies had a high risk of bias resulting from study design limitations. Only one trial [28] reported an adequately generated allocation sequence, and two trials [28,36] reported allocation concealment.…”

Section: Quality Assessmentmentioning

confidence: 99%

“…In the eight studies [15,22,28,29,33,36,41,48] that examined the incidence of adjacent vertebral compression …”

Section: Secondary Outcomesmentioning

confidence: 99%

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Balloon kyphoplasty versus percutaneous vertebroplasty in treating osteoporotic vertebral compression fracture: grading the evidence through a systematic review and meta-analysis

Xing

et al. 2012

Eur Spine J

114

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Objective To assess the safety and efficacy of balloon kyphoplasty (KP) compared with percutaneous vertebroplasty (VP) and provide recommendations for using these procedures to treat osteoporotic vertebral compression fractures (OVCF). Methods A systematic search of all studies published through March 2012 was conducted using the MEDLINE, EMBASE, OVID, ScienceDirect and Cochrane CENTRAL databases. The randomized controlled trials (RCTs) and non-randomized controlled trials that compared KP to VP and provided data on safety and clinical effects were identified. Demographic characteristics, adverse events and clinical outcomes were manually extracted from all of the selected studies. The evidence quality levels and recommendations were assessed using the GRADE system. Results Twelve studies encompassing 1,081 patients met the inclusion criteria. Subgroup meta-analyses were performed according to the study design. In the RCT subgroup, there were significant differences between the two procedures in short-term visual analog scale (VAS), long-term kyphosis angles, operative times and anterior vertebrae heights. In the cohort study subgroup, there were significant differences between the two procedures in short-and longterm VAS, short-and long-term Oswestry Disability Index (ODI), cement leakage rates, short-and long-term kyphosis angles, operative times and anterior vertebrae heights. However, there were no significant differences in long-term VAS or adjacent vertebral fracture rates in the RCT subgroup. There were no significant differences in short-or long-term VAS, short-or long-term ODI, cement leakage rates, adjacent vertebral fracture rates, short-or long-term kyphosis angles or anterior vertebrae heights in the CCT subgroup, and the adjacent vertebral fracture rates did not differ significantly in the cohort study subgroup. The overall GRADE system evidence quality was very low, which lowers our confidence in their recommendations. Conclusions KP and VP are both safe and effective surgical procedures for treating OVCF. KP may be superior to VP in patients with large kyphosis angles, vertebral fissures, fractures in the posterior edge of the vertebral body or significant height loss in the fractured vertebrae. Due to the poor quality of the evidence currently available, highquality RCTs are required.

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“…6). The results of the five trials [15,22,29,36,39] that provided long-term ODI data were consistent with these short-term outcomes (Fig. 7).…”

Section: Primary Outcomessupporting

confidence: 69%

“…A total of 242 titles and abstracts were preliminarily reviewed, of which 12 studies [11,15,17,22,28,29,33,36,39,41,48,49] eventually satisfied the eligibility criteria ( Fig. 1).…”

Section: Search Resultsmentioning

confidence: 99%

Section: Search Resultsmentioning

confidence: 99%

Section: Quality Assessmentmentioning

confidence: 99%

“…In the eight studies [15,22,28,29,33,36,41,48] that examined the incidence of adjacent vertebral compression …”

Section: Secondary Outcomesmentioning

confidence: 99%

See 3 more Smart Citations

Balloon kyphoplasty versus percutaneous vertebroplasty in treating osteoporotic vertebral compression fracture: grading the evidence through a systematic review and meta-analysis

Xing

et al. 2012

Eur Spine J

114

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In vitro assessment of poly(methylmethacrylate)‐based bone cement containing magnetite nanoparticles for hyperthermia treatment of bone tumor

Kawamura

Kawashita

et al. 2012

J Biomedical Materials Res

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Poly(methylmethacrylate) (PMMA)-based cements containing magnetite (C-PMMA/Fe(3)O(4)) is useful in hyperthermia treatment for bone tumor. We have prepared C-PMMA/Fe(3)O(4) by incorporating Fe(3) O(4) powders of different diameters (means of 300, 35, and 11 nm) into the polymerization reaction of methyl methacrylate monomer to develop a new bone cement with high heating efficiencies in alternating current (AC) magnetic fields. Further, we have investigated the in vitro heating capability of the cements in different AC magnetic fields. The mechanical strength and biocompatibility of the resultant cements were also assessed. Their heat generation strongly depends on the magnetite nanoparticle sizes and applied magnetic fields. The cement containing Fe(3)O(4) with mean diameter around 35 nm exhibited the highest heating capability in AC magnetic fields of 120 and 300 Oe at 100 kHz while that with mean diameter around 11 nm exhibited optimum heating capability in AC magnetic fields of 40 Oe at 600 kHz. The incorporation of Fe(3)O(4) into cement-30 wt % of the total amount of cement-did not significantly change the compressive strength of cement, and the proliferation of rat fibroblast Rat-1 cells on cement discs was not inhibited. Our investigations are useful for designing new PMMA/Fe(3)O(4) bone cement with high heating efficiencies and biocompatibilities for bone tumor treatments.

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Kyphoplasty and Vertebroplasty for the Treatment of Pain in the Rehabilitation Patient

McJunkin¹,

Maita²,

Swing³

et al. 2017

Comprehensive Pain Management in the Rehabilitation Patient

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Vertebroplasty and kyphoplasty: complementary techniques for the treatment of painful osteoporotic vertebral compression fractures. A prospective non-randomised study on 154 patients

Cited by 60 publications

References 25 publications

Balloon kyphoplasty versus percutaneous vertebroplasty in treating osteoporotic vertebral compression fracture: grading the evidence through a systematic review and meta-analysis

Balloon kyphoplasty versus percutaneous vertebroplasty in treating osteoporotic vertebral compression fracture: grading the evidence through a systematic review and meta-analysis

In vitro assessment of poly(methylmethacrylate)‐based bone cement containing magnetite nanoparticles for hyperthermia treatment of bone tumor

Kyphoplasty and Vertebroplasty for the Treatment of Pain in the Rehabilitation Patient

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