Vertebral Uptake of Tc-99m Macroaggregated Albumin (MAA) with SPECT/CT Occurring in Superior Vena Cava Obstruction

Karls, Shawn; Hassoun, Hani; Derbekyan, Vilma

doi:10.1007/s13139-015-0372-y

Cited by 3 publications

(2 citation statements)

References 10 publications

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“…In our case, some 99m Tc-MAA particles passed through the vertebral venous plexus by retrograde flow[ 9 ] and were finally trapped by the vertebral capillaries. [ 10 ]…”

Section: Discussionmentioning

confidence: 99%

Vertebral uptake of 99mTc-macroaggregated albumin during lung perfusion scanning

2020

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A 53-year-old female underwent a lung ventilation/perfusion scintigraphy (V/Q scan) in the workup of extensive thrombosis of the left subclavian and internal jugular veins. The perfusion lung scan visualized an atypical uptake in the thoracic vertebrae. A chest Computed Tomography (CT) scan demonstrated unusual tortuous and opacified thoracic superficial veins, collaterals of the lateral thoracic vein. Many venous collateral pathways can be developed in the case of superior vena cava syndrome. 99m Tc-macroaggregated albumin particles may pass through the lateral thoracic vein and eventually through the vertebral venous plexus before being finally trapped by the vertebral capillaries. Besides right-to-left shunting, extrapulmonary uptake in the lung perfusion scintigraphy is very rare and may be used by collateral venous pathways.

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“…In our case, some 99m Tc-MAA particles passed through the vertebral venous plexus by retrograde flow[ 9 ] and were finally trapped by the vertebral capillaries. [ 10 ]…”

Section: Discussionmentioning

confidence: 99%

Vertebral uptake of 99mTc-macroaggregated albumin during lung perfusion scanning

2020

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“…It has been reported that extra-pulmonary accumulation of Tc-99m-MAA was less than 4% among 378 lung scan patients (2). Extra-pulmonary accumulation of Tc-99m-MAA can be detected mostly in the liver as well as the brain, kidney, thyroid, myocardium, spleen and vertebra in several studies (3,4,5,6).…”

mentioning

confidence: 99%

Unexpected Hepatic Uptake of Tc-99m-MAA in Lung Perfusion Scintigraphy in a Patient with End-stage Renal Disease

Kucuker

Güney

Aikimbaev

et al. 2019

Mirt

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Extra-pulmonary accumulation of Tc-99m-macroaggregated albumin (MAA) is described as uptake areas out of the lung in perfusion scintigraphy. If the particles spread throughout the body before reaching the lung via venous collaterals or due to right-to-left shunt, or if the particles are too small to occlude the pulmonary capillaries, then the agent can be seen at different locations of the body. Extra-pulmonary accumulation of Tc-99m-MAA can be detected mostly in the liver as well as in the brain, kidney, thyroid, myocardium, spleen and vertebra. Herein, we present lung scanning images with unexpected hepatic accumulation of Tc-99m-MAA. This pulmonary perfusion scintigraphy was performed in a patient with end-stage renal disease due to dyspnea in the post-operative period of kidney transplantation.

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Superior Vena Cava Syndrome Induced Collateral Circulation on 99mTc–Macroaggregated Albumin Lung Perfusion Scintigraphy

Kersting

Guberina²,

Umutlu

et al. 2020

Clin Nucl Med

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Perfusion lung scintigraphy using SPECT/CT is one mainstay in diagnosing pulmonary embolism. Although typically almost all tracer will be accumulated in the lung capillaries, occasionally abnormal uptake can be detected. As superior vena cava syndrome leads to aberrant blood flow, tracer injected to an arm vein might partly circumvent the pulmonary capillary bed and accumulate in well-perfused anatomical structures. In this case, next to the commonly described liver enhancement, more prominent pseudo-uptake of various thoracic vertebrae was observable. However, a time-related FDG PET/CT demonstrated only the hepatic pseudo-uptake. Taken together, careful assessment of superior vena cava syndrome patient studies is highly recommended.

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Vertebral Uptake of Tc-99m Macroaggregated Albumin (MAA) with SPECT/CT Occurring in Superior Vena Cava Obstruction

Cited by 3 publications

References 10 publications

Vertebral uptake of 99mTc-macroaggregated albumin during lung perfusion scanning

Vertebral uptake of 99mTc-macroaggregated albumin during lung perfusion scanning

Unexpected Hepatic Uptake of Tc-99m-MAA in Lung Perfusion Scintigraphy in a Patient with End-stage Renal Disease

Superior Vena Cava Syndrome Induced Collateral Circulation on 99mTc–Macroaggregated Albumin Lung Perfusion Scintigraphy

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