Vertebral Metastasis of Intraductal Papillary Mucinous Tumor of the Pancreas

Takuma, Yoshitaka; Kawai, Daisuke; Makino, Yasuhiro; Saito, Shuntaro; Tanaka, Shouichi; Ogata, Masatoshi; Ohta, Takeyuki; Murakami, Ichiro; Nishiura, Tsukasa

doi:10.1097/01.mpa.0000232328.28199.d3

Cited by 7 publications

(7 citation statements)

References 8 publications

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“…However, invasive IPMN has a high recurrence and high mortality8). In particular, lymph node metastasis is an important prognostic factor and frequent in patients with invasive IPMNs7). For those patients with invasive IPMNs, 1-, 2-year actuarial survival rates were 45%, 24% with positive lymph nodes, on the other hand 95%, 95% with negative lymph nodes6).…”

Section: Discussionmentioning

confidence: 99%

“…In our case, because of poor prognosis of invasive IPMN with positive lymph node metastasis, we selected subtotal removal of tumor mass as an operative method. Unlike lymph node metastasis, distant metastasis of IPMNs is rare1,7). Liver and lung have been reported as the common sites of distant metastasis7,8).…”

Section: Discussionmentioning

confidence: 99%

“…Unlike lymph node metastasis, distant metastasis of IPMNs is rare1,7). Liver and lung have been reported as the common sites of distant metastasis7,8). In particular, vertebral metastasis of invasive IPMN is extremely rare and only one case has been reported7).…”

Section: Discussionmentioning

confidence: 99%

“…But if we consider metastasis of adenocarcinoma, especially vertebral metastasis of intraductal papillary mucinous neoplasm(IPMN) is rare4,7). IPMN is a pancreatic neoplasm, characterized by production of mucinous fluid, cystic dilatation of the pancreatic ducts, and intrapapillary growth2,8,9).…”

Section: Introductionmentioning

confidence: 99%

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Delayed Epidural Mucin Collection after Surgery for Spinal Metastatic Pancreatic Adenocarcinoma

Kim

Nam

et al. 2017

Korean J Spine

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A rare case of delayed large epidural mucin collection causing neurologic deficit after surgery for metastatic pancreatic cancer is reported. A 65-year-old man presented with intractable upper-thoracic back pain radiating to the chest and gait disturbance. He had a history of subtotal pancreatectomy due to intraductal papillary mucinous neoplasm (IPMN) of the pancreas and concurrent chemotherapy. Eight months after pancreatectomy, multiple thoracic spinal metastasis was diagnosed with routine up positron emission tomography-computed tomography. Radiotherapy for spinal metastasis and subsequent chemotherapy was carried out. Sixteen months after pancreatectomy, gait disturbance occurred and follow-up thoracic magnetic resonance imaging (MRI) showed aggravation of metastasis at T2 and T4 compressing the spinal cord. We performed a decompressive laminectomy with subtotal resection of the tumor masses and pedicle screw fixation at C7–T6. Neurologic status improved after the operation. Histopathologic examinations revealed the tumor as metastatic mucin producing adenocarcinoma. Three months after surgery, motor weakness and pain was reappeared. MRI showed large amount of epidural fluid collection. We performed wound revision and there was large amount of gelatinous fluid at the epidural space. We suggest that postoperative mucin collection and wound problems should be considered after surgery for mucin producing metastatic pancreatic tumor.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Delayed Epidural Mucin Collection after Surgery for Spinal Metastatic Pancreatic Adenocarcinoma

Kim

Nam

et al. 2017

Korean J Spine

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“…In tumors where the response to chemotherapy is slower, as in pancreatic cancer, pain reduction parallels the decrease in pressure exerted on spinal structures as the tumor slowly diminishes in size (Takuma, et al, 2006). However, in very advanced cancer patients there is little justification for using chemotherapy because of its toxicity (Bruera, 1993).…”

Section: Chemotherapymentioning

confidence: 99%