Vertebral fracture assessment by new dual-energy X-ray absorptiometry

Bazzocchi, Alberto; Spinnato, Paolo; Fuzzi, Federica; Diano, Danila; Morselli-Labate, Antonio Maria; Sassi, Claudia; Salizzoni, Eugenio; Battista, Giuseppe; Guglielmi, Giuseppe

doi:10.1016/j.bone.2012.01.018

Cited by 40 publications

(21 citation statements)

References 24 publications

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“…In recent years, many authors have investigated VFs using different imaging modalities, such as radiography, dual-energy Xray absorptiometry and CT [9,14,17,23].…”

Section: Discussionmentioning

confidence: 99%

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Reliability and accuracy of scout CT in the detection of vertebral fractures

Bazzocchi

Fuzzi

Garzillo

et al. 2013

BJR

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Objective: The aim of the present study was to evaluate the reliability of scout CT (sCT) lateral radiograph, in terms of diagnostic accuracy and intra-and interobserver agreement in the detection of vertebral fractures (VFs). Methods: 300 CT examinations of the thoracic and/or lumbar spine were collected and independently analysed by 3 musculoskeletal radiologists in 2 different sessions. A semi-quantitative approach was used for VF assessment on sCT, and morphometric analysis was performed when a VF was suspected. Results of multiplanar sagittal CT reconstructions interpreted by the most expert radiologist were considered as gold standard. Arthrosis was also scored. Only vertebral bodies assessable by both sCT and gold standard were considered for the analysis. Area under the receiver operating characteristic curve (AUROC), Cohen's kappa statistic and linear-by-linear association were used for statistical analysis.

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“…In recent years, many authors have investigated VFs using different imaging modalities, such as radiography, dual-energy Xray absorptiometry and CT [9,14,17,23].…”

Section: Discussionmentioning

confidence: 99%

“…Spine assessment with the aim of VF detection has been performed on the main basis of spine radiographs and dual-energy X-ray absorptiometry scans [9]. In the same way, several methods have been found to semi-quantitatively or quantitatively detect VFs.…”

mentioning

confidence: 99%

Reliability and accuracy of scout CT in the detection of vertebral fractures

Bazzocchi

Fuzzi

Garzillo

et al. 2013

BJR

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“…Furthermore, osteoporotic vertebral fractures can be evaluated through lateral "Dual-energy X-ray absorptiometry" (DXA)-scans, which have been found to be highly sensitive (> 80 %) in detecting moderate/ severe vertebral deformations and have shown excellent negative prognostic values (> 90 %) in differentiating persons without vertebral deformations from those with vertebral deformations. This method is referred to as "vertebral fracture analysis" (VFA) [29,30]. On the other hand, osteo- porotic vertebral fractures can be detected in asymptomatic persons primarily by non-dedicated imaging examinations.…”

Section: Resultsmentioning

confidence: 99%

Impact of Specific Training in Detecting Osteoporotic Vertebral Fractures on Routine Chest Radiographs

Gruber

Dinges

Müller

et al. 2013

Fortschr Röntgenstr

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“…The early diagnosis and prevention of osteoporosis is of great importance, and detecting the bone mineral density (BMD) is the most commonly used clinical method of diagnosis (5,6). Currently, dual-energy X-ray absorptiometry (DXA) is recognized as the gold standard for measuring BMD (7,8); however, the results of BMD provide the sum of minerals in the cortical and cancellous bones, and thus early detection of osteoporosis originating from the vertebral cancellous bone is difficult (9,10). Conventional computed tomography (CT) examination of osteoporosis typically depends on the clinicians experience in detecting trabecular bone rarefraction, vertebral double-concave deformation and density decreases, which cannot accurately reflect the alteration in BMD; therefore, dual-energy quantitative CT may theoretically be the best technique for measuring BMD (11).…”

Section: Introductionmentioning

confidence: 99%

Gemstone spectral imaging for measuring adult bone mineral density

Shao

Liu

2016

Experimental and Therapeutic Medicine

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Abstract. The present study aimed to detect the bone Ca 2+ content of L3 vertebrae in adults by gemstone spectral computed tomography. In total, 235 patients were selected and divided into age groups of 10 years each. The scanning data were used to detect the water-based and Ca 2+ -based substance levels on the L3 vertebral cancellous bone images. The results indicated that there were significant differences in vertebral Ca 2+ -water and water-Ca 2+ densities determined by gemstone spectral imaging (GSI) between males and females in subjects aged 50-59 years, 60-69 years, 70-79 years and ≥80 years (P<0.05). The ages of male and female participants were negatively correlated with vertebral Ca 2+ -water density (P<0.01) and water-Ca 2+ density (P<0.01). In conclusion, GSI may be used as a novel method of measuring the vertebral adult bone mineral density.

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Vertebral fracture assessment by new dual-energy X-ray absorptiometry

Cited by 40 publications

References 24 publications

Reliability and accuracy of scout CT in the detection of vertebral fractures

Reliability and accuracy of scout CT in the detection of vertebral fractures

Impact of Specific Training in Detecting Osteoporotic Vertebral Fractures on Routine Chest Radiographs

Gemstone spectral imaging for measuring adult bone mineral density

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