Vertebral bone mineral density of the elderly in the urban community by mobile DXA

Abstract

Abstract:The present paper describes a population survey of bone mineral density (BMD) on the third lumbar vertebra (L3) using dual X-ray absorptiometry fixed in a van (mobile DXA) with lateral projection. Subjects were 387 persons aged 65 to 84 years living in Koganei City, a western suburb of Tokyo. This is the baseline survey of the 10-year project "Longitudinal Interdisciplinary Study on Aging" supported by Tokyo Metropolitan Institute of Gerontology (TMIG-LISA). As for the pattern of age-related BMD calculated in the range-of-interest (ROI) being set in the center of vertebral body to eliminate the posterior segment of vertebra and/or secondary hyperostotic changes with aging, the mean BMD of L3 declined in females from 0.514+-0.121g/cm ~ (mean _+ standard deviation) in age-group 65-69 to 0.377+--0.137 g/cm 2 in age-group 80-84. In males, it showed a decrease from 0.731--+0.155 in 65-69 to 0.613--+0.158 in 75-79 hut a slight (insignificant) increase at age-group 80-84. There were significant differences of mean BMD between males and females in each age-group and in average. BMD was significantly associated with age (negatively) and body mass index (positively) in the multiple regression analysis.

Low bone mineral density at femoral neck is a predictor of increased mortality in elderly Japanese women

“…BMD was measured at the femoral neck and trochanter using dual-energy X-ray absorptiometry (DXA), with the Hologic QDR-1000 densitometer (Hologic, Waltham, MA, USA), and was used as a mobile DXA [24]. The coefficient of variation for hip BMD was 1.6% for the femoral neck and 1.5% for the trochanter [25].…”