Versuche über Pflanzenhybriden

Mendel, Gregor

doi:10.1007/978-3-663-19714-0

Cited by 81 publications

(97 citation statements)

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“…iv. As expected under genetic laws (Mendel 1866;Druery and Bateson 1901), we did not confirmed that hth plants can be a source of pollen or ovule bearing an HTH allele.…”

contrasting

confidence: 72%

Outcrossing as an Explanation of the Apparent Unconventional Genetic Behavior ofArabidopsis thaliana hthMutants

Mercier¹,

Jolivet²,

Vignard³

et al. 2008

Genetics

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The reappearance of HTH alleles in the offspring of homozygous Arabidopsis hth mutants is not consistent with classical Mendelian genetics. It has been suggested that stored RNA may be used to restore genetic information. However, Peng et al. reported that hth mutants tend to display outcrossing and suggested that outcrossing might provide an alternative explanation for the apparent genetic instability. We have confirmed and extended these results, corroborating that the apparent non-Mendelian behavior of hth mutants can be explained by their susceptibility to outcrossing.

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“…iv. As expected under genetic laws (Mendel 1866;Druery and Bateson 1901), we did not confirmed that hth plants can be a source of pollen or ovule bearing an HTH allele.…”

contrasting

confidence: 72%

Outcrossing as an Explanation of the Apparent Unconventional Genetic Behavior ofArabidopsis thaliana hthMutants

Mercier¹,

Jolivet²,

Vignard³

et al. 2008

Genetics

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“…History of the gene, 1860 to just before ENCODE Definition 1860s-1900s: Gene as a discrete unit of heredity spring-that is, these traits are passed on as distinct, discrete entities (Mendel 1866). His work also demonstrated that variations in traits were caused by variations in inheritable factors (or, in today's terminology, phenotype is caused by genotype).…”

Section: Introductionmentioning

confidence: 99%

What is a gene, post-ENCODE? History and updated definition

et al. 2007

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While sequencing of the human genome surprised us with how many protein-coding genes there are, it did not fundamentally change our perspective on what a gene is. In contrast, the complex patterns of dispersed regulation and pervasive transcription uncovered by the ENCODE project, together with non-genic conservation and the abundance of noncoding RNA genes, have challenged the notion of the gene. To illustrate this, we review the evolution of operational definitions of a gene over the past century-from the abstract elements of heredity of Mendel and Morgan to the present-day ORFs enumerated in the sequence databanks. We then summarize the current ENCODE findings and provide a computational metaphor for the complexity. Finally, we propose a tentative update to the definition of a gene: A gene is a union of genomic sequences encoding a coherent set of potentially overlapping functional products. Our definition sidesteps the complexities of regulation and transcription by removing the former altogether from the definition and arguing that final, functional gene products (rather than intermediate transcripts) should be used to group together entities associated with a single gene. It also manifests how integral the concept of biological function is in defining genes.

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“…According to Mendel's second Law [1], alleles of different genes assort independently of one another during gamete formation. In sexually reproducing species, random transmission of paternal and maternal genomes is achieved by the independent segregation of chromosomes during meiosis.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Mendelian and clonal genome transmission in a sexually reproducing, all-triploid vertebrate

et al. 2011

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Meiosis in triploids faces the seemingly insuperable difficulty of dividing an odd number of chromosome sets by two. Triploid vertebrates usually circumvent this problem through either asexuality or some forms of hybridogenesis, including meiotic hybridogenesis that involve a reproductive community of different ploidy levels and genome composition. Batura toads (Bufo baturae; 3n ¼ 33 chromosomes), however, present an all-triploid sexual reproduction. This hybrid species has two genome copies carrying a nucleolus-organizing region (NORþ) on chromosome 6, and a third copy without it (NOR2). Males only produce haploid NORþ sperm, while ova are diploid, containing one NORþ and one NOR2 set. Here, we conduct sibship analyses with co-dominant microsatellite markers so as (i) to confirm the purely clonal and maternal transmission of the NOR2 set, and (ii) to demonstrate Mendelian segregation and recombination of the NORþ sets in both sexes. This new reproductive mode in vertebrates ('pre-equalizing hybrid meiosis') offers an ideal opportunity to study the evolution of non-recombining genomes. Elucidating the mechanisms that allow simultaneous transmission of two genomes, one of Mendelian, the other of clonal inheritance, might shed light on the general processes that regulate meiosis in vertebrates.

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Versuche über Pflanzenhybriden

Cited by 81 publications

References 0 publications

Outcrossing as an Explanation of the Apparent Unconventional Genetic Behavior ofArabidopsis thaliana hthMutants

Outcrossing as an Explanation of the Apparent Unconventional Genetic Behavior ofArabidopsis thaliana hthMutants

What is a gene, post-ENCODE? History and updated definition

Simultaneous Mendelian and clonal genome transmission in a sexually reproducing, all-triploid vertebrate

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