Developing
a respiratory analysis disease diagnosis platform for
the H2S biomarker has great significance for the real-time
detection of various diseases. However, achieving highly sensitive
and rapid detection of H2S gas at the parts per billion
level at low temperatures is one of the most critical challenges for
developing portable exhaled gas sensors. Herein, Cu2O-multiwalled
carbon nanotube (MWCNT) heterostructures with excellent gas sensitivity
to H2S at room temperature and a lower temperature were
successfully synthesized by a facile two-dimensional (2D) electrodeposition
in situ assembly method. The combination of Cu2O and MWCNTs
via the principle of optimal conductance growth not only reduced the
initial resistance of the material but also provided an ideal interfacial
barrier structure. Compared to the response of the pure Cu2O sensor, that of the Cu2O-MWCNT sensor to 1 ppm of H2S increased nearly 800 times at room temperature, and the
response time decreased by more than 500 s. In addition to the excellent
sensitivity with detection limits as low as 1 ppb, the Cu2O-MWCNT sensor was extremely selective with low-temperature adaptability.
The sensor had a response value of 80.6 to 0.1 ppm of H2S at −10 °C, which is difficult to achieve with sensors
based on oxygen adsorption/desorption mechanisms. The sensor was used
for the detection of real oral exhaled breath, confirming its feasibility
as a real-time disease monitoring sensor. The Cu2O-MWCNT
heterostructures maximized the advantages of the individual components
and laid the experimental foundation for future applications of highly
sensitive portable breath analysis platforms for monitoring H2S.