Versatile, High Quality and Scalable Continuous Flow Production of Metal-Organic Frameworks

Abstract

Further deployment of Metal-Organic Frameworks in applied settings requires their ready preparation at scale. Expansion of typical batch processes can lead to unsuccessful or low quality synthesis for some systems. Here we report how continuous flow chemistry can be adapted as a versatile route to a range of MOFs, by emulating conditions of lab-scale batch synthesis. This delivers ready synthesis of three different MOFs, with surface areas that closely match theoretical maxima, with production rates of 60 g/h at extremely high space-time yields.

Tailoring Physical Aging in Super Glassy Polymers with Functionalized Porous Aromatic Frameworks for CO2 Capture

“…PTMSP membranes loaded with functionalized PAF-1 rivaled as-cast membranes where handling and treatment of PTMSP mixed matrix membranes has been optimized and yet remain prone to aging. 3-5, 30, 31 Coupled with the capability to mass-produce porous nanoparticles 32 and their selective-aging properties, these membranes are highly attractive for a range of separation challenges. …”

Continuous flow production of metal-organic frameworks

“…This was achieved without a loss in yield or product quality. Through systematic identification and optimisation of the key factors influencing the synthesis of MOFs via continuous flow methods, it has been demonstrated that fast synthesis can be achieved without a loss in product quality, and moreover with the ability to control the product's particle size [29 ].…”

“…Reproduced from Faustini et al [46 ] Centre: Schematic representation of the continuous synthesis system used for the instant production of HKUST-1 MOF. Reprinted with permission from the work of Gimeno-Fabra et al [26 ] Right: Schematic representation showing the general flow reactor for the production of MOFs.Reprinted with permission from the work of Rubio-Martinez et al[29 ].…”

Towards scalable and controlled synthesis of metal–organic framework materials using continuous flow reactors

“…40 The groups of Rubio-Martinez et al 38 and Taddei showing massive expansion or contraction once water, or other guest molecule is removed from the pores, after the material has been prepared. 41 Bayliss et al produced MIL-53(Al) using the sodium salt of terephthalic acid and water as the solvent, 37 while Taddei et al used DMF as solvent in their continuous microwave reactor, giving much superior space-time yields.…”