Vers un diagnostic biologique de la maladie d’Alzheimer et des syndromes apparentés

Krolak‐Salmon, Pierre; Seguin, J.; Perret‐Liaudet, Armand; Desestret, Virginie; Vighetto, Alain; Bonnefoy, Marc

doi:10.1016/j.revmed.2008.01.029

Cited by 3 publications

(1 citation statement)

References 121 publications

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“…Their presence is difficult to monitor, specifically in different body fluids like blood and cerebrospinal fluid (CSF) 2, 3. Standard immunoenzymatic tests are not sensitive enough to give reliable identification in the ante mortem stage due to the extremely low concentrations of these proteins 4–7. Moreover, Perret‐Liaudet et al8 noticed a great loss of phosphorylated Tau protein (pTau181), Tau, and Aβ‐42 peptide on the inner walls of sampling tubes with time, leading to false titration values.…”

Section: Introductionmentioning

confidence: 99%

Non‐Adhesive Behavior of New Nanostructured PNIPAM Surfaces Towards Specific Neurodegenerative Proteins: Application to Storage and Titration of Tau Proteins

Vrlinič

Debarnot

Legeay

et al. 2012

Macromolecular Bioscience

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New nonfouling tubes are developed and their influence on the adhesion of neuroproteins is studied. The biomarkers are considered as single components (recombinant prion and Tau proteins) or in a solution of native and pathological forms. The samples are stored for 24 h at 4 °C in virgin and treated tubes layered with two different nanostructured coatings based on poly(N-isopropylacrylamide) with either a positive or a neutral charge, and the protein adhesion is monitored. The recombinant protein with a high pI is repelled from the nanostructured surface that has a negative ζ potential, whereas the recombinant protein with the lower pI is attracted. Furthermore, in the case of complex solutions, neutral nanostructured surfaces are able to retain all amyloid biomarkers.

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Section: Introductionmentioning

confidence: 99%

Non‐Adhesive Behavior of New Nanostructured PNIPAM Surfaces Towards Specific Neurodegenerative Proteins: Application to Storage and Titration of Tau Proteins

Vrlinič

Debarnot

Legeay

et al. 2012

Macromolecular Bioscience

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Current awareness in geriatric psychiatry

2009

Int J Geriat Psychiatry

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of geriatric psychiatry. Each bibliography is divided into 9 sections: 1 Reviews; 2 General; 3 Assessment; 4 Epidemiology; 5 Therapy; 6 Care; 7 Dementia; 8 Depression; 9 Psychology. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted

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Évaluation des procédures diagnostiques de la maladie d’Alzheimer : une revue systématique des méta-analyses

Letrilliart

Roubaud

Lainé

et al. 2012

cah. année gerontol.

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Vers un diagnostic biologique de la maladie d’Alzheimer et des syndromes apparentés

Cited by 3 publications

References 121 publications

Non‐Adhesive Behavior of New Nanostructured PNIPAM Surfaces Towards Specific Neurodegenerative Proteins: Application to Storage and Titration of Tau Proteins

Non‐Adhesive Behavior of New Nanostructured PNIPAM Surfaces Towards Specific Neurodegenerative Proteins: Application to Storage and Titration of Tau Proteins

Current awareness in geriatric psychiatry

Évaluation des procédures diagnostiques de la maladie d’Alzheimer : une revue systématique des méta-analyses

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