Verification of simulation of surface texturing on planar surface by grinding

Kim, Ho-Chan; Ko, Tae Jo

doi:10.1007/s12541-015-0030-4

Cited by 15 publications

(4 citation statements)

References 21 publications

(28 reference statements)

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“…An array of 36 MNs was used to coat 9 µl of drug formulation and only 40% of the loaded drug was delivered. Surface texturing on the needle surface via electromechanical machining methods could be employed to increase the needle's surface area [14][15][16][17][18]; however, only marginal increases in the surface area have been achieved. Specifically, Ryu [14] achieved approximately 200 nm² size craters on the surface area by electromechanical machining methods [14].…”

Section: Introductionmentioning

confidence: 99%

Porous polymer coatings on metal microneedles for enhanced drug delivery

Ullah

Kim

2018

R. Soc. open sci.

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We present a simple method to coat microneedles (MNs) uniformly with a porous polymer (PLGA) that can deliver drugs at high rates. Stainless steel (SS) MNs of high mechanical strength were coated with a thin porous polymer layer to enhance their delivery rates. Additionally, to improve the interfacial adhesion between the polymer and MNs, the MN surface was modified by plasma treatment followed by dip coating with polyethyleneimine, a polymer with repeating amine units. The average failure load (the minimum force sufficient for detaching the polymer layer from the surface of SS) recorded for the modified surface coating was 25 N, whereas it was 2.2 N for the non-modified surface. Calcein dye was successfully delivered into porcine skin to a depth of 750 µm by the porous polymer-coated MNs, demonstrating that the developed MNs can pierce skin easily without deformation of MNs; additional skin penetration tests confirmed this finding. For visual comparison, rhodamine B dye was delivered using porous-coated and non-coated MNs in gelatin gel which showed that delivery with porous-coated MNs penetrate deeper when compared with non-coated MNs. Finally, lidocaine and rhodamine B dye were delivered in phosphate-buffered saline (PBS) medium by porous polymer-coated and non-coated MNs. For rhodamine B, drug delivery with the porous-coated MNs was five times higher than that with the non-coated MNs, whereas 25 times more lidocaine was delivered by the porous-coated MNs compared with the non-coated MNs.

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Section: Introductionmentioning

confidence: 99%

Porous polymer coatings on metal microneedles for enhanced drug delivery

Ullah

Kim

2018

R. Soc. open sci.

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“…Additionally, the characteristics of traditional LAG limit the use of coolant and also cannot fundamentally eliminate surface/subsurface cracks due to heat accumulation [12] and [13]. These problems have become the bottleneck limiting the application of LAG [14] and [15].…”

Section: Highlights • the Research Is Focused On Analysing The Laser-mentioning

confidence: 99%

Laser-Induced Deterioration Grinding of Zirconium Oxide (ZrO2) – Generation of Layer Patterns and Performance Evaluation

Zhang

Deng²,

Ren

et al. 2015

SV-JME

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Laser-induced deterioration was proposed for the wet grinding of zirconium oxide (ZrO 2) ceramic used in the dental, semiconductor and automotive industries. The mechanisms for laser induced deterioration and wet grinding of the deterioration layer were theoretically analysed, and the four key processing parameters that determine the micro-topography and distribution of the laser-induced crater were proposed, including the laser power density I p , the defocus distance z, the laser spot overlap ratio U s and the laser scanning track line overlap ratio U l. Further, the forming mechanism of the single pulse-induced crater under different laser power densities, the defocus distance, and the interaction mechanisms between adjacent spots along the longitudinal and transverse directions were investigated. The optimal values of the key processing parameters were identified. To further evaluate the effect of laser-induced deterioration objectively, a comparative experiment was conducted under laser-induced deterioration wet grinding (LIDWG) and conventional grinding (CG) conditions. It was found that the procedure of laser-induced deterioration had a strong influence on the grinding results. The normal and tangential grinding forces for LIDWG condition were lower than for CG condition, with a maximum reduction of 59.2 % (62.9 %).

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“…Grinding brings various advantages for large-area texturing as compared to other techniques (such as abrasive jet machining, etching, lasers, and mechanical cutting and rolling). Depending on the type of patterns to be created on a workpiece, the grinding wheel requires specific geometries, such as different grooves on the peripheral surface of the wheel [3]. Surface textures on the wheels are used to improve the tribological qualities of frictional surfaces together with the aesthetic and tactile qualities of items [4].…”

Section: Introductionmentioning

confidence: 99%

Investigation of the effect of wheel grooves on surface grinding performance in EN18 Steel

Jeyakumar,

Krishnamoorthy

2023

Preprint

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The grooved grinding wheels are utilized to enhance the coolant supply to the grinding zone and reduce the heat throughout grinding, thus making the grinding performance more efficient. In the present study, Al2O3 grinding wheels of axial, circumferential and helical grooved wheels were used to grind the EN18 steel. The input parameters chosen for experiments were types of grooved grinding wheels, depth of cut with three different coolant techniques (Dry, Flood and MQL) and experiments were conducted as per L9 Taguchi orthogonal matrix. Output parameters measured for each experiment were grinding ratio (GR), material removal rate (MRR), grinding efficiency (GE), surface roughness (Ra), specific energy (SE), temperature and noise during surface grinding. The grinding performance of non-grooved grinding wheels was compared with a grooved wheel. The results showed that using grooved grinding wheels increases all the grinding performances when compared to the non-grooved grinding wheel. The helical grooved wheel with MQL combinations reduced the temperature, sound, surface roughness and specific energy from 35.8 to 32.1 °C, 86.9 to 80.7 dB, 1.584 to 0.258 µm and 0.173 to 0.054 kJ/mm2 respectively. At the same time, the MRR, HRC, GR and GE were improved using grooved grinding wheels along with MQL from 0.432 to 1.37 mm3/s, 58.5 to 61.5 HRC, 1.77 to 4.567 and 10.26 to 43.9% respectively. Finally, the optimum grinding parameter combination was identified from a helical grooved wheel in all grinding performances. Finally, the performance of the helical grooved wheel was compared with non-grooved wheels. SEM images were taken to understand the surface finish and defects on the ground surfaces for the different wheels with coolants.

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Verification of simulation of surface texturing on planar surface by grinding

Cited by 15 publications

References 21 publications

Porous polymer coatings on metal microneedles for enhanced drug delivery

Porous polymer coatings on metal microneedles for enhanced drug delivery

Laser-Induced Deterioration Grinding of Zirconium Oxide (ZrO2) – Generation of Layer Patterns and Performance Evaluation

Investigation of the effect of wheel grooves on surface grinding performance in EN18 Steel

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