Vergleich klinischer und radiologischer Daten bei der Behandlung von Patienten mit osteoporotischen Wirbelkörper-Kompressionsfrakturen mit Radiofrequenz-Kyphoplastie oder mit Ballon-Kyphoplastie

Pflugmacher, Robert; Bornemann, Rahel; Koch, Ernst; Randau, Thomas M.; Müller-Broich, J. D.; Lehmann, U.; Weber, O.; Wirtz, Dieter Christian; Kabir, K.

doi:10.1055/s-0031-1280122

Cited by 26 publications

(17 citation statements)

References 8 publications

(8 reference statements)

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“…Additionally, RF-TVA consistently showed a well-identified focal area of PMMA with an extensive peripheral zone of PMMA interdigitation, providing mechanical interlock into the adjacent intact trabecular matrix. Additionally, several retrospective studies of RF-TVA for treatment of VCFs have demonstrated consistent improvements in back pain severity and ODI and no procedural complications [15–17]. The results of these studies and of the current prospective study provide increasing evidence that treatment with RF-TVA is optimized by the targeted delivery and interdigitation of ultrahigh viscosity RF-heated cement into the remaining trabeculae.…”

Section: Discussionmentioning

confidence: 53%

Prospective Single-Site Experience with Radiofrequency-Targeted Vertebral Augmentation for Osteoporotic Vertebral Compression Fracture

Moser

Maya

Blaszkiewicz

et al. 2013

Journal of Osteoporosis

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Vertebral augmentation procedures are widely used to treat osteoporotic vertebral compression fractures (VCFs). We report our initial experience with radiofrequency-targeted vertebral augmentation (RF-TVA) in 20 patients aged 50 to 90 years with single-level, symptomatic osteoporotic VCF between T10 and L5, back pain severity > 4 on a 0 to 10 scale, Oswestry Disability Index ≥ 21%, 20% to 90% vertebral height loss compared to adjacent vertebral body, and fracture age < 6 months. After treatment, patients were followed through hospital discharge and returned for visits after 1 week, 1 month, and 3 months. Back pain severity improved 66% (P < 0.001), from 7.9 (95% CI: 7.1 to 8.6) at pretreatment to 2.7 (95% CI: 1.5 to 4.0) at 3 months. Back function improved 46% (P < 0.001), from 74 (95% CI: 69% to 79%) at pretreatment to 40 (95% CI: 33% to 47%) at 3 months. The percentage of patients regularly consuming pain medication was 70% at pretreatment and only 21% at 3 months. No adverse events related to the device or procedure were reported. RF-TVA reduces back pain severity, improves back function, and reduces pain medication requirements with no observed complications in patients with osteoporotic VCF.

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Section: Discussionmentioning

confidence: 53%

Prospective Single-Site Experience with Radiofrequency-Targeted Vertebral Augmentation for Osteoporotic Vertebral Compression Fracture

Moser

Maya

Blaszkiewicz

et al. 2013

Journal of Osteoporosis

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“…We saw one case of adjacent vertebral fracture (2.2 %) during the follow-up examination after 12 months. This is a good result compared to the adjacent fracture rates of 0 -8 % for vertebroplasty and 25 -26 % for kyphoplasty (follow-up period of 3 -12 months) for stabilized osteoporotic vertebral compression fractures [10,27] and 0 -18 % [6, 28] for vertebroplasty and 2.9 -18 % for kyphoplasty (follow-up period of 9 -12 months) for stabilized tumorous vertebral fractures [6,17,28]. This may indicate a change in the biomechanics of a vertebral body stabilized with the Osseofix ® system compared to one stabilized exclusively with bone cement [11].…”

Section: Special Complicationsmentioning

confidence: 79%

Osseofix® System for Percutaneous Stabilization of Osteoporotic and Tumorous Vertebral Compression Fractures – Clinical and Radiological Results After 12 Months

Ender

Gradl²,

Ender

et al. 2013

Fortschr Röntgenstr

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Purpose: Determining whether implantation of an expandable titanium mesh cage (Osseofix? system) is a successful and safe minimally invasive therapy for osteoporotic and tumorous vertebral compression fractures (VCFs). Materials and Methods: 32 patients (25 women, 7 men, mean age 71) with 46 osteoporotic or tumorous VCFs (T6 to L4) from June 2010 to January 2012 were included. All of them were stabilized with the Osseofix? system. Preinterventionally we performed X-ray, MRI, and bone density measurements (DXA). The clinical and radiological results were evaluated preop, postop and 12 months postop based on the visual analog scale (VAS) and the Oswestry Disability Index (ODI), X-ray (Beck Index, Cobb angle) and CT. Results: There was a significant improvement in pain intensity (VAS) (7.8 to 1.6) as well as a?significant reduction in the mean ODI (71.36?% to 30.4?%) after 12 months. The mean kyphotic angle according to Cobb showed significant improvements (12.3? to 10.8?) after 12 months. Postinterventional imaging showed one case of loss of height in a stabilized lumbar vertebral body (2.2?%) in osteoporosis and one case with adjacent fracture (2.2?%) in osteoporosis. We saw no changes in the posterior vertebral wall. Except for one pronounced postoperative hematoma, we saw no surgical complications including no cement leakage. Conclusion: The clinical mid-term results are good at a low complication rate. The stabilization of symptomatic osteoporotic and tumorous VCFs with the Osseofix? system is a safe and effective procedure, even in fractures with posterior wall involvement. The Osseofix? system is an interesting alternative to the established procedures of cement augmentation. Key Points: ??The Osseofix? system is well suited for stabilizing osteoporotic and tumorous VCFs. ??It is a safe and effective procedure without cement leakage and with a low complication rate. ??The procedure is an interesting alternative to established cement augmentation procedures. Citation Format: ??Ender SA, Gradl G, Ender M et?al. Osseofix? System for Percutaneous Stabilization of Osteoporotic and Tumorous Vertebral Compression Fractures ? Clinical and Radiological Results After 12 Months. Fortschr R?ntgenstr 2014; 186: 380???387

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“…There were 5 studies from Germany [8,9,24,26,27] and 1 study from USA. [25] The extracted studies included 2 RCTs, [9,24] 1 prospective cohort studies, [26] and 3 retrospective cohort studies. [8,25,27] Five studies were published in English while 1 was in German.…”

Section: Resultsmentioning

confidence: 99%

“…[8,25,27] Five studies were published in English while 1 was in German. [26] The majority of the included patients suffered from osteoporotic VCF, and meanwhile malignant and traumatic VCF were involved in a part of the studies. There was no significant difference in age and gender between the 2 groups ( P > .05).…”

Section: Resultsmentioning

confidence: 99%

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Comparison of radiofrequency kyphoplasty (RFK) and balloon kyphoplasty (BKP) in the treatment of vertebral compression fractures

Feng

Shen²,

Feng³

et al. 2017

Medicine

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Background:Balloon kyphoplasty (BKP) is a widely adopted minimally invasive treatment for vertebral compression fractures (VCFs), but leakage of cement is a main complication of BKP. A novel vertebral augmentation technique radiofrequency kyphoplasty (RFK) with high viscosity cement was developed in 2009. Here, we aim to evaluate whether RFK can relieve symptoms efficiently and reduce cement leakage.Methods:A literature search was performed using Pubmed, Embase, and Cochrane CENTRAL until September 30, 2016. Both randomized controlled trial (RCT) and non-RCT studies comparing RFK and BKP were included. The main outcomes included pain relief (VAS), functionality improvement (ODI), operation time, reduction of deformity (vertebral height and kyphosis angle), and incidence of cement leakage. The origin of heterogeneity was further explored by subgroup stratification.Results:A total of 6 studies involving 833 patients with VCFs were included. The reduction of VAS score in the RFK group was 3.96 points more than that in the BKP group (P = .0007) postoperatively, and the improvement persisted until 12 months after the surgery (P < .00001). The operation time was shorter in RFK group than that in BKP group (P = .01). The increase of anterior vertebral height shortly after the operation was 0.53 mm greater in RFK group (P = .01). The decrease of kyphotic angle after RFK was 0.63° and 0.92° greater than that after BKP, both immediately and 6 months after operation (P = .002 and P < .00001, respectively). There was no significant difference between the incidence of cement leakage after RFK and BKP (P = .06). Further subgroup analysis stratified by study design indicated that the incidence of leakage decreased 15% in RFK than BPK (P < .00001) in non-RCT subgroup, but RFK and BKP treatments were equivalent in the RCT studies (P = .86).Conclusion:RFK appears to be more effective and safer than BKP in the present meta-analysis. The incidence of cement leakage diverges in RCT and non-RCT studies, so large-sample multicentered RCT studies are required to validate this new surgery system.

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Vergleich klinischer und radiologischer Daten bei der Behandlung von Patienten mit osteoporotischen Wirbelkörper-Kompressionsfrakturen mit Radiofrequenz-Kyphoplastie oder mit Ballon-Kyphoplastie

Cited by 26 publications

References 8 publications

Prospective Single-Site Experience with Radiofrequency-Targeted Vertebral Augmentation for Osteoporotic Vertebral Compression Fracture

Prospective Single-Site Experience with Radiofrequency-Targeted Vertebral Augmentation for Osteoporotic Vertebral Compression Fracture

Osseofix® System for Percutaneous Stabilization of Osteoporotic and Tumorous Vertebral Compression Fractures – Clinical and Radiological Results After 12 Months

Comparison of radiofrequency kyphoplasty (RFK) and balloon kyphoplasty (BKP) in the treatment of vertebral compression fractures

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