Affect and meaningfulness in verbal mediation were studied. The design of the study included Phase I, which varied the affect levels (high and low) while holding meaningfulness constant at a medium level, and Phase II, which varied both the affect level (high and low) of the mediators and the level of meaningfulness (high and low) of the non-mediators. Results showed that high-affect mediators produced superior mediation and that an affect by meaningfulness interaction occurred. High affect was more potent than high meaningfulness in producing superior mediation.