Verapamil inhibits 3T3-L1 preadipocyte differentiation

Gu, Nan; Shi, Liu; Guo, Xirong; Fei, Li; Xiao-qin, Pan; Guo, Ming; Chen, Ronghua

doi:10.1016/s1007-4376(09)60090-3

Cited by 9 publications

(10 citation statements)

References 16 publications

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“…[ 19 ] The direct reductive amination of glucose with secondary amines is a more efficient route to N , N ‐dialkylglucamine derivatives but it has rarely been reported so far. [ 20 ] Direct reductive amination of glucose with secondary amines gives different reaction products ranging from alkylated glucamines to C 2 ‐ or C 3 ‐amino alcohols, generated by retro aldol reactions. [ 21 ] The outcome of these conversions is dependent on the reductive reagents used and reaction conditions.…”

Section: Materials and Methods/experimentalmentioning

confidence: 99%

Glucamines as green alternatives to conventional amino alcohols in metalworking fluids

Seddig

Naundorf

Kipphardt

et al. 2022

Materials & Corrosion

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Amino alcohols like triethanolamine (TEA), 2‐amino‐2‐methylpropanol (AMP), or 1‐aminopropan‐2‐ol (MIPA) are common ingredients in industrial metalworking fluids. They are used in large quantities as alkaline additives for the neutralization of acidic corrosion inhibitors and are typical industrial products from the oil‐based value chain. The criteria for the selection of these additives have changed in the last decades and are nowadays not only performance‐driven but influenced by ecological considerations, toxicity, and regulatory standards. In this study, we evaluate the sugar derivative N,N‐diethylglucamine (DEGA) for use as a functional, nonvolatile, chemically stable, and cheap alkaline additive for common acidic corrosion inhibitors. Electrochemical analyses confirm anticorrosive properties of DEGA comparable to the gold standard TEA for iron and steel in an aqueous environment at a slightly alkaline pH. In addition, DEGA leads to extremely low levels of Co, Ni, and Cu leaching and can thus also serve as a nonvolatile substitute for currently used low‐leaching additives such as AMP and MIPA. The diethylamino‐motif is a sweet spot among different glucamine derivatives tested because it combines easy synthetic accessibility with good water solubility and low‐leaching properties. Besides this, DEGA can be prepared in one step from glucose and diethylamine, both derived from renewable resources.

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Section: Materials and Methods/experimentalmentioning

confidence: 99%

Glucamines as green alternatives to conventional amino alcohols in metalworking fluids

Seddig

Naundorf

Kipphardt

et al. 2022

Materials & Corrosion

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“…Early childhood health mainly contains physical and mental level health. (Gu, 2009) Integration did not go to explore the theory of rural health curriculum resource development, so the health curriculum resource development is all castles in the air, into a source of water (Liu, 2021).…”

Section: Uneven Development Of Rural Early Childhood Teachers' Health...mentioning

confidence: 99%

Research on the Problems and Improvement Strategies of Rural Early Childhood Teachers' Health Education Competence

Meng

2024

CETR

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The health concept of the new era calls for the return and renewal of the identity of rural early childhood teachers, as health educators, what makes them competent in their professional roles? The health education ability of rural early childhood teachers has become an important factor affecting the physical and mental health of rural young children. This study points out that the development of rural early childhood teachers' health education ability is not balanced, rural early childhood teachers' health education curriculum resources development ability is weak, and it points to the lack of rural early childhood teachers' family health education guidance ability. Therefore, based on the analysis of the problem, we start by updating the concept of health education for rural early childhood teachers, establishing the evaluation system of rural early childhood teachers' health education ability, integrating the rural early childhood health education resources, and carrying out rural early childhood health education garden-based teaching and research. Therefore, based on the analysis of the problem, we put forward the strategies to improve the health education ability of rural kindergarten teachers from four aspects: updating the health education concept of rural kindergarten teachers, establishing the evaluation system of rural kindergarten teachers' health education ability, integrating rural kindergarten health education resources, conducting rural kindergarten health education garden-based teaching and research and reflection.

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“…Laminar flame propagation velocity is an important parameter to reflect the combustion characteristics, which can characterize whether the premixed combustion process is intense [49,50]. Figure 9 shows the comparison between the simulated and experimental values of laminar flame velocities of n-decane, α-methylnaphthalene, IDEA reference fuel and hydrogen.…”

Section: Laminar Flame Speedsmentioning

confidence: 99%

Study on the Combustion Mechanism of Diesel/Hydrogen Dual Fuel and the Influence of Pilot Injection and Main Injection

Dong

Liu

et al. 2023

Processes

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Hydrogen is a clean and renewable alternative fuel. In this paper, the combustion mechanism of diesel/hydrogen dual fuel is constructed and verified. The mechanism is combined with three-dimensional numerical simulation to study the effects of pilot injection and main injection on the combustion and emissions of a diesel/hydrogen dual fuel engine. The mechanism uses a 70% mole fraction of n-decane and 30% mole fraction of α-methylnaphthalene as diesel substitutes, and it combines n-decane, α-methylnaphthalene, NOX, PAH, soot and H2/C1-C3 sub-mechanisms to form a diesel/hydrogen dual fuel combustion mechanism. The mechanism was verified by chemical kinetics, including the ignition delay time, JSR (Jet Stirred Reactor) oxidation and laminar flame speed, and then, it was verified by computational fluid dynamics. The results show that the simulated values are in good agreement with the experimental values of cylinder pressure, heat release rate and emissions data. The mechanism can well predict the combustion and emissions of a diesel/hydrogen dual fuel engine. Compared with single injection, the peak heat release rate, peak cylinder pressure and MPIR (Maximum Pressure Rise Rate) increase with the increase in pilot mass percent from 5% to 20%, which makes the phase of CA10 and CA50 advance and reduces CO emissions, but NOX emissions increase. With the advance of pilot injection timing from 10° CA BTDC to 30° CA BTDC, the peak cylinder pressure increases, the peak heat release rate decreases, CA10 and CA50 advance, CO emissions decrease, NOX emissions increase and NOX emissions peak at 30° CA BTDC. When the pilot injection timing is further advanced from 30° CA BTDC to 50° CA BTDC, the peak cylinder pressure decreases, the peak heat release rate increases, CA10 and CA50 are delayed, CO and NOX emissions are reduced, and NOX emissions at 50° CA BTDC are lower than those at 10° CA BTDC. With the advance of main injection timing from 0° CA BTDC to 8° CA BTDC, CO emissions decrease, NOX emissions increase, the peak cylinder pressure increases, the peak heat release rate decreases slightly first and then increases, and the peak cylinder pressure and peak heat release rate corresponding to the overall phase shift forward. When the main injection timing is advanced to 6° CA BTDC, MPIR is 1.3 MPa/° CA, exceeding the MPIR limit of diesel engine 1.2 MPa/° CA.

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Verapamil inhibits 3T3-L1 preadipocyte differentiation

Cited by 9 publications

References 16 publications

Glucamines as green alternatives to conventional amino alcohols in metalworking fluids

Glucamines as green alternatives to conventional amino alcohols in metalworking fluids

Research on the Problems and Improvement Strategies of Rural Early Childhood Teachers' Health Education Competence

Study on the Combustion Mechanism of Diesel/Hydrogen Dual Fuel and the Influence of Pilot Injection and Main Injection

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