Ventriculo-Sinus Transversal Shunt in the Treatment of Decompensated Hydrocephalus in Children (The Results of Clinical Testing of the Method)

Хачатрян, В. А.; Samochernykh, Konstantin; Ким, А. В.; Nikolaenko, Mikhail Sergeevich; Sysoev, Kirill; Дон, О. А.; Шаповалов, А. С.; Абрамов, К. Б.; Іванов, В. П.; Kobozev, V.V.

doi:10.18705/2311-4495-2017-4-1-20-28

Cited by 5 publications

(7 citation statements)

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“…An increase in the treatment effectiveness under VSS is achieved by restoring intracranial circulation and CSF absorption at the stage of prolonged sanitation of craniospinal CSF spaces with saline solution in combination with VSGD and LP. There is a high percentage of dysfunction and complications after VPS [6][7][8][9][12][13][14].…”

Section: Discussionmentioning

confidence: 99%

“…At present, much attention is paid to the study of posthemorrhagic hydrocephalus in newborns [1][2][3][4][5][6][7][8][9][10][11][12][13][14]. It is noted that the formation of hydrocephalus is due to direct occlusion of the cerebrospinal fluid by blood clots, or dynamic occlusion by means of the subarachnoid space (SAS) compression, impaired absorption of cerebrospinal fluid (CSF) with indications, at the initial stage, for lumbar punctures (LP), ventricular punctures (VP) with 20-22G needles, as well as puncture drainage of the lateral ventricles [1][2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

“…LP-VSGD-VPS). The relevance of the problem is that there is no generally accepted opinion regarding the treatment of decompensated hydrocephalus [6][7][8] with the need to personalize treatment tactics aimed at restoring CSF dynamics [2], reducing the incidence of VPS and system dysfunction [9][10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

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Posthemorrhagic Hydrocephalus With Decompensation Of Cerebrospinal Fluid Dynamics In Newborns: New In Treatment Tactics

2020

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Background ― Posthemorrhagic hydrocephalus in newborns with occlusion of cerebrospinal fluid leads to decompensation of cerebrospinal fluid dynamics. There is no single method that meets all the criteria for the effectiveness and safety of treatment. The study goal was to investigate the use of coronary translambdoid subarachnoid ventriculostomy (CTSV) and ventricular subarachnoid stenting (VSS) in the treatment of neonatal hydrocephalus. Material and Methods ― The analysis of the posthemorrhagic hydrocephalus treatment in 327 newborns for the period of 2000-2018 in Crimea. Two groups have been identified. In the Group 1, 184 children underwent standard treatment according to the ‘LVV protocol’ with lumbar and ventricular punctures with 20-22G needles, while with progression of hydrocephalus, with ventriculosubgaleal drainage and ventriculoperitoneal shunt. In 143 children with occlusion and ventricular block, the treatment complex included CTSV – RF Patent No. 2715535, and ventricular drainage by the ventricular subarachnoid stenting (VSS) – RF Patent No. 2721455. Results ― An increase in the treatment radicality under CTSV is achieved through the use of the cerebral needles of a larger diameter (14G) and puncture access zones, elimination of occlusion, while under VSS, restoration of intracranial circulation and absorption of cerebrospinal fluid is ensured by prolonged sanitation with a saline solution of cerebrospinal fluid spaces. A positive outcome with compensation for hydrocephalus was achieved in 75.4% of cases versus 28.2% under the conventional protocol (p<0.001). In other cases, the imbalance of production and absorption of cerebrospinal fluid remained, which required the integration of the VSS with the peritoneal segment of the shunt, without further replacement and reinstallation of the system. Conclusion ― Our results allow us to consider the effectiveness of CTSV and VSS inclusion in the contemporary algorithm for the treatment of decompensated posthemorrhagic hydrocephalus in newborns.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Posthemorrhagic Hydrocephalus With Decompensation Of Cerebrospinal Fluid Dynamics In Newborns: New In Treatment Tactics

2020

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“…На поздних этапах развития гидроцефалии происходят структурно-функциональные изменения мозга (избыточное скопление ликвора, расширение и деформация ликворных полостей и венозной системы мозга, увеличение внутричерепного давления), которые и создают условия для формирования патологической системы, провоцирующей в дальнейшем неблагоприятное течение заболевания [7,10,12].…”

Section: заключениеunclassified

“…В настоящее время наиболее распространенным методом лечения является вентрикулоперитонеостомия в сочетании с эндоскопическими вмешательствами [5][6][7][8][9][10][11]. В других случаях операцией выбора считается вентрикулоатриостомия [12,13].…”

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The treatment of patients with posthemorrhagic hydrocephalus

Samochernykh

Abramov

Nikolaenko

et al. 2021

Ross. vestn. perinatol. pediatr.

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The article discusses the possible causes of polycystic posthemorrhagic ventriculomegaly in infants, as well as predictors of this pathological process. When choosing a treatment method the doctor shall take into account not only the etiology of the disease, but also age parameters, concomitant pathology. An important aspect in the approach to the treatment of polycystic posthemorrhagic multilevel hydrocephalus includes the determination of the biomechanical properties of the craniospinal system, especially the compliance of the brain and resorption of cerebrospinal fluid. Particular attention is paid to the timely correction of complications, including the analysis of inflammatory changes markers in the craniospinal system, which serve as predictors of the outcome of cerebrospinal fluid resorption. The authors also noted that the violation of the cerebrospinal fluid outflow from the cranial cavity in children may depend on a large number of «extracerebral» factors. They consider the stages of neurosurgical care to patients in this group on a clinical example. This example and literature data demonstrate that children with age develop changes not only in the craniospinal segment, which is responsible for the transformation of free fluid, but also in the extracranial cavities. Thus, we are able to recommend an integrated approach for the management of newborns with intracranial hemorrhage, complicated by posthemorrhagic hyporesorbent and occlusive hydrocephalus, with the justification of the optimal neurosurgical tactics for managing drainage-dependent patients, the course of the disease in which is accompanied by a multicomponent inflammatory syndrome.

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Tumor Immunity as Well as Its Treatment Methods

Bao

2020

IOP Conf. Ser.: Earth Environ. Sci.

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in the passing years, tumor immunotherapy has become a major research topic and up till now, some remarkable progress has been achieved. It has come up with a new oncotherapy method different from surgery, conventional chemoradiotherapy. Tumor immunotherapy aims to kill or inhibit tumor growth by activating the immune system of the human body itself or enhancing the functions of the immune system. This thesis reviews the research and development of oncolytic virus therapy, CAR-T therapy and phytochemical drug therapy.

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Ventriculo-Sinus Transversal Shunt in the Treatment of Decompensated Hydrocephalus in Children (The Results of Clinical Testing of the Method)

Cited by 5 publications

References 2 publications

Posthemorrhagic Hydrocephalus With Decompensation Of Cerebrospinal Fluid Dynamics In Newborns: New In Treatment Tactics

Posthemorrhagic Hydrocephalus With Decompensation Of Cerebrospinal Fluid Dynamics In Newborns: New In Treatment Tactics

The treatment of patients with posthemorrhagic hydrocephalus

Tumor Immunity as Well as Its Treatment Methods

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