Ventricular Fibrillation Complicating Acute Myocardial Infarction

Lawrie, D.M.; Higgins, Michael R.; Godman, M J; Oliver, M.F.; Julian, Desmond G.; Donald, K. W.

doi:10.1016/s0140-6736(68)92403-3

Cited by 207 publications

(24 citation statements)

References 23 publications

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“…The findings of higher rates of VF/CA in older (60 or more years) versus younger MI subjects is in contrast with results of previous studies (Julian et al, 1964;Lawrie, 1969;Lawrie et al, 1968). For example, Lawrie (1969) and also Julian er al.…”

Section: Resultscontrasting

confidence: 98%

“…Because of the high case-fatality rate (CFR) associated with ventricular fibrillation or cardiac arrest (VF/CA) complicating an acute myocardial infarction (MI) (Dixon, 1970;Fabricius-Bjerre et al, 1974;Goldberg et al, 1979a;Hill et al, 1973), the identification of patients a t high risk for development of these arrhythmias has been attempted by examining their relationship to clinical and demographic variables (Lawrie, 1969;Lawrie et al, 1968;Lie et al, 1974). However, the results have been equivocal, perhaps due to selection biases affecting the choice of the study samples which, in general, have included clinical series from single institutions.…”

Section: Introductionmentioning

confidence: 99%

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Predictors of ventricular fibrillation or cardiac arrest in patients hospitalized for acute myocardial infarction

Tonascia

Szklo

Goldberg

et al. 1981

Clinical Cardiology

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A community-wide study of patients hospitalized with acute myocardial infarction in metropolitan Baltimore was conducted to examine socio-demographic and clinical characteristics in association with ventricular fibrillation and cardiac arrest (VF/CA). Multivariate analyses revealed that variables significantly associated with occurrence of VF/CA included older age (60 years or older), male sex, and a history of cigarette smoking. These factors allow the identification of subgroups of patients hospitalized with acute myocardial infarction at high risk for the subsequent development of VF/CA, in whom prophylactic therapy and close surveillance are especially recommended

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Section: Resultscontrasting

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Predictors of ventricular fibrillation or cardiac arrest in patients hospitalized for acute myocardial infarction

Tonascia

Szklo

Goldberg

et al. 1981

Clinical Cardiology

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“…27 Secondary ventricular fibrillation in the presence of severe but not uniformly fatal CHF could lead to a mortality rate as high as 70%. 1,28 The poor outcome of our patients with severe CHF and cardiac arrest in our series could also be explained by factors described earlier.…”

Section: Discussionmentioning

confidence: 57%

Acute Myocardial Infarction in the Eastern Province of Saudi Arabia: Retrospective Analysis of 264 Patients

et al. 1990

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The medical records of all patients (N = 264) admitted to King Fahd Hospital with a confirmed diagnosis of acute myocardial infarction (AMI) between January 1982 and December 1987 were retrospectively reviewed. A total of 221 males (84%) and 43 females (16%) were identified. Median age was 53.2 ± 12.3 years. Saudi patients constituted 61% of the patients, and Indians and Pakistanis were the most frequent nationalities among non-Saudis (16%), Current smoking history (57%), past medical history of coronary heart disease (48%), and diabetes mellitus (28%) were the most common risk factors encountered. Of all the patients, 54 (20%) died in hospital from AMIrelated complications. Logistic regression analysis identified cardiogenic shock, cardiac arrest, and development of severe congestive heart failure (CHF) as three adverse factors that, independently, influenced in-hospital mortality. Over a median follow-up of 32 months, 208 patients were analyzed for long-term survival. The survival curve estimated that at 36 months the survival probability (±SE) was 0.78 ± 0.06 (95% confidence interval, 66 to 90%). The multivariate proportional hazard of Cox revealed that age above 60 years, severe CHF, and withholding longacting nitrates were the only significant covariates that independently influenced long-term survival adversely. Our data indicate that efforts to combat smoking should be intensified. Furthermore, the baseline information obtained from our analysis should be compared with that derived from our newly established coronary care unit. The data also indicate that the prospective evaluation of the protective role of long-acting nitrates is warranted.

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“…5 Neither stood the test of time. 6,7 The CCU was also the testing site for appraising the value of pharmacological and nonpharmacological interventions in reducing infarct size with ␤-blocking agents, thrombolytic agents, or primary angioplasty. Reducing infarct size has also helped to lower the incidence of postinfarction ventricular arrhythmias.…”

Section: The Ccumentioning

confidence: 99%