Ventricular Asynchrony of Time‐to‐Peak Systolic Velocity in Structurally Normal Heart by Tissue Doppler Imaging

Sadeghian, Hakimeh; Ahmadi, F; Lotfi‐Tokaldany, Masoumeh; Kazemisaeid, Ali; Fathollahi, Mahmood Sheikh; Goodarzynejad, Hamidreza

doi:10.1111/j.1540-8175.2010.01156.x

Cited by 10 publications

(8 citation statements)

References 24 publications

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“…The authors found that systole and diastole within the left ventricle were "highly synchronized" but the time to isovolumic and peak systolic velocities of the right ventricle were -comparable to our data with reservations -slightly delayed. In a study by Sadeghian et al (2010), the time to peak systolic velocity of basal septal and lateral left ventricle was measured in 65 "healthy young adult volunteers" (30.1±7.5 years, 52 % male) and also septal to lateral delay (equivalent to LV-IntraSys-1 and LV-IntraSys-2 with reservations) was calculated (Sadeghian et al 2010). Mean values of time to peak systolic velocities of basal septal and lateral ventricle differed by ≈45 ms and calculated mean septal to lateral delay was 55±39 ms. A similar septal to lateral delay (median 66 ms, by measuring time to peak systolic velocities as well) was reported by Miyazaki et al (2008) in a study including 40 "healthy subjects" (age 47±15 years, 60 % male).…”

Section: Discussionmentioning

confidence: 98%

Evaluation of Left and Right Ventricular Systolic and Diastolic Electromechanical Synchrony in Older People: a Population-Based Observational Study

Laszlo

Konz²,

Kunz³

et al. 2017

Physiol Res

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It is unknown whether physiological ageing also goes along with electromechanical asynchrony of contraction. Aim of the study was to evaluate synchrony of contraction in older people with (“non-healthy”) or without (”healthy”) evidence for structural cardiac disease. In 547 persons (age 76.7±5.5 years, 306 male, 241 female) recruited from a population-based cohort of the ActiFE-Ulm study including a random sample of people ≥65 years old living in the region of Ulm, Germany, various PW- and TDI-Doppler based markers for asynchrony were obtained by echocardiography. Within a subgroup of 84 healthy subjects, at most minimal systolic and diastolic asynchrony was found. Concerning systolic asynchrony, similar observations were made within the non-healthy subgroup. However, extent of diastolic left ventricular intraventricular asynchrony and also – by tendency – diastolic interventricular asynchrony was increased in comparison to the healthy subgroup. To conclude, no evidence that physiological ageing might go along with relevant left or right ventricular systolic or diastolic electromechanical asynchrony was found in our study. Furthermore, our population-based data support the results from other clinical studies with rather selected cohorts that structural heart diseases might go along with increased diastolic asynchrony.

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Section: Discussionmentioning

confidence: 98%

Evaluation of Left and Right Ventricular Systolic and Diastolic Electromechanical Synchrony in Older People: a Population-Based Observational Study

Laszlo

Konz²,

Kunz³

et al. 2017

Physiol Res

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“…Although Gimenes et al6 have published reference values for real‐time transthoracic three‐dimensional echocardiographic dyssynchrony indexes in a normal population, such data are still lacking CHF patients. As there is no agreed on standardization currently available for evaluating LVSS,7–12 there is increasing interest for a novel method that would allow real‐time, convenient, accurate, and reproducible LVSS measurements. We evaluated the feasibility of assessing LVSS by RT‐3DE, in comparison with TDI.…”

Section: Discussionmentioning

confidence: 99%

Real‐time three‐dimensional echocardiographic evaluation of left ventricular systolic synchronicity in patients with chronic heart failure: Comparison with tissue doppler imaging

Liang

Cao

et al. 2012

J of Clinical Ultrasound

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“…Measuring the time difference in peak systolic velocity in septum and lateral wall from TDI, often referred to as the septal-lateral delay , is both robust and feasible, and one of the most established methods [17]. Also derived from TDI, the ratio between the sum of the isovolumetric relaxation and isovolumetric contraction times devided by contraction time, often referred to as the myocardial performance index (MPI) can be calculated, this index is similar to the Tei index, but the latter is not derived from TDI.…”

Section: Methodsmentioning

confidence: 99%

The prognostic value of mechanical left ventricular dyssynchrony in patients with acute coronary syndrome

Westholm

Johnson

Jernberg

et al. 2013

Cardiovasc Ultrasound

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BackgroundEchocardiography is a well-established tool for risk stratification in patients with acute coronary syndrome (ACS). ACS has significant impact on LV dyssynchrony, and detrimental effects on systolic function and long term outcome. The aims of this study were to determine whether LV dyssynchrony carries any predictive information in an unselected ACS population and to evaluate if it has any incremental value to the information given from conventional echocardiographic measurements.MethodsThe study included 227 consecutive ACS patients. Primary endpoint was the composite of death, new MI, or rehospitalisation due to heart failure. Dyssynchrony was measured as intersegmental variation of time to peak strain, the post systolic index (PSI) and myocardial performance index (MPI) with the standard deviation and difference between lowest and highest value (delta) expressing the amount of dyssynchrony. Septal-lateral delay was also tested. All dyssynchrony parameters were compared with Ejection fraction (EF).ResultsThe median follow up time was 53 months. 85 patients reached the combined endpoint. Patients with and without a subsequent combined endpoint differed significantly regarding calculated SD: s and delta-value for PSI, time to peak 2D-strain and MPI but not regarding septal-lateral delay. In ROC-analysis none of the dyssynchrony parameters had larger AUC than EF. When adjusting for traditional risk factors none of the dyssynchrony parameters remained associated with outcome, whereas EF still did.ConclusionLV dyssynchrony seem to have significant prognostic information in patient with acute coronary syndrome but in comparison to conventional parameters such as EF there is no incremental value of this information.

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Ventricular Asynchrony of Time‐to‐Peak Systolic Velocity in Structurally Normal Heart by Tissue Doppler Imaging

Abstract: Normal population almost had dyssynchrony by previously described markers and many of these markers were more frequent in women. Conducting more studies on normal population by other tissue Doppler modalities may give better description of cardiac synchronicity.

Cited by 10 publications

References 24 publications

Evaluation of Left and Right Ventricular Systolic and Diastolic Electromechanical Synchrony in Older People: a Population-Based Observational Study

Evaluation of Left and Right Ventricular Systolic and Diastolic Electromechanical Synchrony in Older People: a Population-Based Observational Study

Real‐time three‐dimensional echocardiographic evaluation of left ventricular systolic synchronicity in patients with chronic heart failure: Comparison with tissue doppler imaging

The prognostic value of mechanical left ventricular dyssynchrony in patients with acute coronary syndrome

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