Ventricular Assist Devices

McDivit, Anna M.; Copeland, Jack G.; Adler, Eric

doi:10.1016/b978-0-12-801238-3.00195-1

Cited by 1 publication

(1 citation statement)

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“…These CADs can be surgically implanted or percutaneously placed into the human body for artificially enhancing the cardiovascular circulation for a certain period. As an effective and widely used CAD, VAD can help to reduce the burden on the heart and maintain blood flow ( Givertz, 2011 ), including left ventricular assist device (LVAD), right ventricular assist device (RVAD) and the biventricular assist device (BiVAD) ( McDivit et al, 2014 ). VAD is usually a pump-type device that pumps the blood from the ventricle to the subsequent vessels.…”

Section: Introductionmentioning

confidence: 99%

Mock circulatory loop applications for testing cardiovascular assist devices and in vitro studies

Gao

Wan³

et al. 2023

Front. Physiol.

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The mock circulatory loop (MCL) is an in vitro experimental system that can provide continuous pulsatile flows and simulate different physiological or pathological parameters of the human circulation system. It is of great significance for testing cardiovascular assist device (CAD), which is a type of clinical instrument used to treat cardiovascular disease and alleviate the dilemma of insufficient donor hearts. The MCL installed with different types of CADs can simulate specific conditions of clinical surgery for evaluating the effectiveness and reliability of those CADs under the repeated performance tests and reliability tests. Also, patient-specific cardiovascular models can be employed in the circulation of MCL for targeted pathological study associated with hemodynamics. Therefore, The MCL system has various combinations of different functional units according to its richful applications, which are comprehensively reviewed in the current work. Four types of CADs including prosthetic heart valve (PHV), ventricular assist device (VAD), total artificial heart (TAH) and intra-aortic balloon pump (IABP) applied in MCL experiments are documented and compared in detail. Moreover, MCLs with more complicated structures for achieving advanced functions are further introduced, such as MCL for the pediatric application, MCL with anatomical phantoms and MCL synchronizing multiple circulation systems. By reviewing the constructions and functions of available MCLs, the features of MCLs for different applications are summarized, and directions of developing the MCLs are suggested.

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Section: Introductionmentioning

confidence: 99%