Ventilation heterogeneity after COVID-19

Savushkina, Olga; Черняк, А. В.; Зайцев, А. В.; Kryukov, Evgeniy

doi:10.1183/13993003.congress-2021.oa2681

Cited by 3 publications

(1 citation statement)

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“…S avushkina et al [ 1 ] presented findings from a cross-sectional study investigating the influence of COVID-19 on ventilation heterogeneity. The study used the multiple-breath nitrogen washout test in post-COVID subjects with no chronic respiratory disease and examined the relationship between the lung clearance index (LCI) and pulmonary function parameters.…”

Section: Group 901: Respiratory Function Technologists and Scientistsmentioning

confidence: 99%

ERS International Congress 2021: highlights from the Allied Respiratory Professionals assembly

et al. 2022

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Section: Group 901: Respiratory Function Technologists and Scientistsmentioning

confidence: 99%

ERS International Congress 2021: highlights from the Allied Respiratory Professionals assembly

et al. 2022

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Functional disorders of the respiratory system after a new coronavirus infection COVID-19

Савушкина¹,

Zaytsev

Kryukov³

et al. 2022

Russian Military Medical Academy Reports

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COVID-19 (Coronavirus disease 2019) is an infectious disease caused by the coronavirus SARS-CoV-2, characterized by a high level of morbidity and mortality. A new coronavirus infection affects all organs and systems and often occurs with lung damage and respiratory failure. In a significant part of patients after the acute period of COVID-19, the symptoms of the disease persist, but the most problematic symptoms are the ones regarding lung damage that persists for a long amount of time. This review summarizes the results of our research in 20202021. The purpose of the conducted studies was to estimate the functional parameters of the respiratory system in patients that have been infected by COVID-19. Along with conventional pulmonary function tests (spirometry, body plethysmography and diffusion test), impulse oscillometry, the multiple-breath nitrogen washout test, determination of the maximum inspiratory and expiratory pressures were performed in all patients. Thus, we evaluated the ventilation and gas exchange function of the bronchopulmonary system, the functional state of the peripheral parts of the lungs, including the small airways, the uniformity of pulmonary ventilation and the strength of the respiratory muscles in different periods of recovery after COVID-19, including the follow-up after medical rehabilitation. To sum up, comprehensive functional assessment of the respiratory system is an important clinical tool that allows the planning of pharmacotherapy and to create individual programs of medical rehabilitation of patients who had COVID-19.

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Methods for diagnosing dysfunction of small airways and uniformity of lung ventilation: their use after a novel coronavirus infection

Савушкина

Черняк

2022

Bûlletenʹ fiziologii i patologii dyhaniâ

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In this lecture, we discussed methods and approaches to the diagnosis of small airways dysfunction, such as multiple breath nitrogen washout test, impulse oscillometry, as well as the calculation of poorly communicating fraction (PCF) as the ratio of total lung capacity to alveolar volume. The detection of the small airways dysfunction with the help of the diagnostic tools listed above makes it possible to establish functional disorders of the respiratory system in the early stages of bronchopulmonary diseases, when the results of traditional pulmonary functional tests remain within normal values. Thus, a well-standardized and the most accessible method for detecting the peripheral airways dysfunction is body plethysmography, which is used to diagnose the presence of “air trappings”. However, in the early stages of bronchopulmonary diseases, the possibilities of this method are limited. The lecture focuses primarily on the results of our own researches which were performed on patients who have suffered from a novel coronavirus infection complicated by viral pneumonia. Spirometry, body plethysmography, diffusion test, impulse oscillometry, multiple breath nitrogen washout test were conducted, and PCF index was calculated in all patients included in this analysis. The description of the PCF index, the method of its calculation, the range of normal values, as well as the possibilities of application in clinical practice are given for the first time in the Russian literature. The approaches to assessing the dysfunction of the small airways described in the lecture are not widely used at present, however, we hope that the knowledge that is currently being applied in scientific laboratories will gradually be introduced into routine clinical practice.

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Ventilation heterogeneity after COVID-19

Cited by 3 publications

References 0 publications

ERS International Congress 2021: highlights from the Allied Respiratory Professionals assembly

ERS International Congress 2021: highlights from the Allied Respiratory Professionals assembly

Functional disorders of the respiratory system after a new coronavirus infection COVID-19

Methods for diagnosing dysfunction of small airways and uniformity of lung ventilation: their use after a novel coronavirus infection

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