Venöz Ayak Ülser Tedavisinde Güncel Yaklaşımlar

Asgarpour, Hosseın

doi:10.22312/sdusbed.560995

Cited by 6 publications

(6 citation statements)

References 10 publications

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“…[8] Bu etkilerinden dolayı yapılan çalışmalarda VAC sistemleri venöz ülser tedavisinde faydalı bulunmuştur. [9][10][11][12]…”

Section: Discussionunclassified

Efficiency of the vacuum-assisted closure method in the treatment of chronic venous ulcers and the role of the nurse

Özşen¹

2022

Cardiovasc Perf Nurs

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Objectives: In our study, it was aimed to reveal the effects of using vacuum-assisted closure (VAC) systems in addition to compression therapy on wound healing in patients hospitalized for chronic venous ulcers. Patients and methods: Fifty-five patients (37 males, 18 females; mean age: 43±5 years, range, 38 to 48 years) who were hospitalized in our clinic for chronic venous ulcers between January 2015 - December 2021 were included in this retrospective study. The demographic data, wound widths, healing times of venous ulcers, length of hospital stay, and surgical treatment methods of patients who did (Group 1) and did not (Group 2) receive VAC therapy in addition to the surgical and medical procedures in the treatment of venous ulcers were compared. Results: The hospital stay of all patients was 9±2 days. While the mean ulcer healing time was 14±2 days in Group 1, it was 48±8 days in Group 2 (p=0.03). The mean hospital stay of the patients was 8±2 days in Group 1, whereas it was 15±3 days in Group 2 (p=0.04). Conclusion: As a result of the study, it was revealed that VAC therapy greatly increased the effectiveness of venous surgical methods and compression therapy in the treatment of chronic venous ulcers and shortened the treatment period; therefore, VAC therapy should be added to the treatment protocol for suitable patients with chronic venous ulcers.

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“…[8] Bu etkilerinden dolayı yapılan çalışmalarda VAC sistemleri venöz ülser tedavisinde faydalı bulunmuştur. [9][10][11][12]…”

Section: Discussionunclassified

Efficiency of the vacuum-assisted closure method in the treatment of chronic venous ulcers and the role of the nurse

Özşen¹

2022

Cardiovasc Perf Nurs

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“…In cancer treatment, biological therapies, such as chemotherapy, radiotherapy, hormone therapy, surgery, immunotherapy, and gene therapy, are used alone or in combination. 1 , 2 …”

Section: Introductionmentioning

confidence: 99%

Silently Proliferating: Cancer

Çoban¹,

Dincer²,

Kose³

2023

Eurasian J Med

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Cancer is a health problem that has existed for years and frequently affects tissues and organs. Although some standards have been set for its treatment, different treatments and approaches are used for each type of cancer. The treatment process and having to live with cancer drag the individual to a difficult process that affects the individual negatively. Problems such as the severe course of the disease, taking longer than expected treatment, and having many side effects reduce the individual's physical performance and activities of daily living. Therefore, this situation reduces the quality of life and causes the general well-being of the individual to be negatively affected at the psycho-social level. In order to cope with the problems that cancer patients experience, it is important to support them physically, mentally, emotionally, socio-culturally, and spiritually. The decrease in the quality of life of the caregiver also affects the quality of care and therefore the quality of life of the patient. For this reason, it is necessary to determine how patients and caregivers perceive the disease, reduce their psychological anxiety and pain, as well as the factors affecting this perception, and ensure their compliance with treatment.

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“…Kanser meydana geldiği dokuya göre ya da köken aldığı hücre çeşidine göre sınıflandırılmaktadır. Kanserin 100'den fazla türü olduğu bilinmektedir (Weinberg, 1996;Baykara, 2016).…”

Section: Introductionunclassified

“…Kontrollü hücre ölümünden yani apoptozdan kaçabilme kanser hücrelerinin bir diğer özelliğidir. Kanser hücreleri genetik ve epigenetik olarak kararlı olmadıkları gibi fenotipik olarak da hücre profilleri değişkenlik göstermektedir (Baykara, 2016). Hannahan (2022) son derlemesinde kanser hücrelerinin 10 temel özelliğine 4 yeni özellik daha eklemiştir.…”

Section: Introductionunclassified

Kalkon Türevlerinin Antikanser Mekanizmaları

YILDIZ,

ARI

2023

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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Kanser; hücrelerin kontrolsüz çoğalmalarına, immün sistemin gözetiminden kaçmalarına ve uzaktaki dokuları istila ederek yayılmalarına yol açan, metabolik değişiklikler geçirdikleri bir süreçtir. Hayatı boyunca her beş kişiden biri, yaşamının bir döneminde kansere yakalanmaktadır. Geliştirilmiş olan tüm tedavi yöntemlerine rağmen, hala kanserin neden olduğu ölümler gelişmiş toplumlarda ikinci sırada yer almaktadır. Kemoterapik tedavilerde kanser hücresinin farklı metabolik yolaklarına etki eden çok çeşitli ilaçlar kullanılmaktadır. Anti-neoplastik özelliği ile bilinen paklitaksel ve dosetaksel gibi birçok bitkisel kökenli anti-kanser ilaç klinikte kullanılmaktadır. Bitkisel kökenli kemoterapötik ajanların çeşitli kanser türlerine karşı tedavi olanakları araştırılmaya devam edilmektedir. Son dönemlerde yapılan çalışmalarda, kanser tedavisinde farklı moleküler yolakları hedefleyebilen flavonoid bazlı bileşikler sentezlenmiştir. Flavonoid ailesine ait olan kalkonlarında farklı biyolojik etkilerinin yanı sıra anti-kanser aktiviteye sahip oldukları belirlenmiştir. Kalkon bileşiklerinin etki mekanizmasını ortaya çıkarmak için bilimsel araştırmalar devam etmektedir. Bu derlemede, kalkon türevlerinin anti-proliferasyon, apoptoz indüksiyonu, mikrotübül polimerizasyonu, anti-anjiyogenezis ve hücre döngüsünün durdurulması gibi mekanizmalar yoluyla anti-kanser rollerinden bahsedilmektedir.

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Venöz Ayak Ülser Tedavisinde Güncel Yaklaşımlar

Cited by 6 publications

References 10 publications

Efficiency of the vacuum-assisted closure method in the treatment of chronic venous ulcers and the role of the nurse

Efficiency of the vacuum-assisted closure method in the treatment of chronic venous ulcers and the role of the nurse

Silently Proliferating: Cancer

Kalkon Türevlerinin Antikanser Mekanizmaları

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