Venovenous extracorporeal membrane oxygenation for acute lung failure in adults

Schmid, Çhristof; Philipp, Alois; Hilker, Michael; Rupprecht, Leopold; Arlt, Matthias; Keyser, Andreas; Lubnow, Matthias; Müller, Thomas

doi:10.1016/j.healun.2011.07.013

Cited by 92 publications

(77 citation statements)

References 20 publications

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“…Additionally, the best outcome was noted in trauma patients. [16] In our study, we found no predictive factor for ECMO mortality, possibly due to small sample size.…”

Section: Discussioncontrasting

confidence: 72%

“…In their study, the weaning rate from ECMO was found to be 67%, overall survival to discharge rate to be 52%, and survival to discharge rate for vv-ECMO support to be 59.5%. In addition, Schmid et al [16] reported their case series consisting of 176 adult patients with acute lung failure treated with vv-ECMO. The overall survival rate was 56% in their series.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: our single-center experience

Yüksel¹

2017

Turk Gogus Kalp Dama

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ÖZAmaç: Bu çalışmada, akut solunum sıkıntısı sendromunun tedavisinde venovenöz ekstrakorporeal membran oksijenasyonuna ilişkin beş yıllık deneyimimiz sunuldu.Ça lış ma pla nı: Kasım 2010 -Kasım 2015 tarihleri arasında konvansiyonel tedaviye dirençli akut solunum sıkıntısı sendromlu 33 hastaya (24 erkek, 9 kadın; ort. yaş 48.6±14.7 yıl; dağılım 19-76 yıl) venovenöz ekstrakorporeal membran oksijenasyonu desteği uygulandı. Venovenöz ekstrakorporeal membran oksijenasyonu desteğinin genel endikasyonu, konvansiyonel tedavinin optimizasyonuna rağmen, refrakter hipoksi, hiperkapni ve solunumsal asidoz idi. Hastaların detaylı klinik verileri retrospektif olarak incelendi. Bul gu lar:Kanülasyon 24 hastada (%73) femoral-femoral venlerden, dokuz hastada (%27) juguler-femoral venlerden gerçekleştirildi. Ortalama venovenöz ekstrakorporeal membran oksijenasyon desteği 17 (dağılım, 1-52) gün idi. En sık görülen komplikasyon, altı hastada (%18) minör kanama idi. On sekiz hasta (%54.5) başarılı bir şekilde venovenöz ekstrakorporeal membran oksijenasyonu desteğinden ayrıldı. Bu hastaların 13'ü (%39.4) sağkaldı ve hastaneden taburcu edildi.So nuç: Venovenöz ekstrakorporeal membran oksijenasyonu, şiddetli akut solunum sıkıntısı sendromlu hastalarda hayat kurtarıcı bir tedavi yöntemi olabilir. Sonuçların iyileşmesi, deneyimlerin artması ve venovenöz ekstrakorporeal membran oksijenasyonunun tedavisine yönelik standart bir protokolün oluşturulması ile sağlanabilir.Anah tar söz cük ler: Akut solunum sıkıntısı sendromu; hayat kurtarıcı modalite; venovenöz ekstrakorporeal membran oksijenasyonu. ABSTRACTBackground:In this study, we present our five-year experience with venovenous extracorporeal membrane oxygenation for the treatment of acute respiratory distress syndrome.

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“…Additionally, the best outcome was noted in trauma patients. [16] In our study, we found no predictive factor for ECMO mortality, possibly due to small sample size.…”

Section: Discussioncontrasting

confidence: 72%

Section: Discussionmentioning

confidence: 99%

Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: our single-center experience

Yüksel¹

2017

Turk Gogus Kalp Dama

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“…Among these, age9, 18, 21, 22, 23, 24 and SOFA score21, 22, 23, 24 were found to be particularly closely associated with hospital mortality and were independent prognostic factors in ARDS patients receiving ECMO support. Roch et al 22.…”

Section: Discussionmentioning

confidence: 95%

Respiratory extracorporeal membrane oxygenation for severe sepsis and septic shock in adults: a propensity score analysis in a multicenter retrospective observational study

Takauji

Hayakawa

Ono

et al. 2017

Acute Medicine & Surgery

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AimThis multicenter retrospective observational study aimed to evaluate the efficacy of extracorporeal membrane oxygenation (ECMO) support for septic patients with severe respiratory failure using propensity score analyses.MethodsThe data of severe sepsis patients from 42 intensive care units between January 2011 and December 2013 were retrospectively collected. Propensity score matching analyses were undertaken for severe respiratory failure patients with/without veno‐venous ECMO support. The main outcome was in‐hospital all‐cause mortality.ResultsOf 3195 patients with severe sepsis, 570 had severe respiratory failure. Forty patients in the ECMO group were matched with 150 patients in the control group. A survival time analysis revealed no difference in the in‐hospital survival (hazard ratio, 0.854; 95% confidence interval, 0.531–1.373; P = 0.515). Two‐hundred and eighty‐five patients had severe respiratory failure induced by lung infection. Twenty‐five ECMO group patients were matched with 89 patients in the control group. In the ECMO group, the survival time was longer than in the control group (hazard ratio, 0.498; 95% confidence interval, 0.279–0.889; P = 0.018). The number of renal replacement therapy‐ and vasopressor‐free days improved. The ECMO group received more red blood cells transfused than the control group, but there was no significant difference in the rate of severe bleeding complications between the groups.ConclusionsThere was no difference in the in‐hospital survival between the ECMO group and control group among overall septic patients with severe respiratory failure. However, in sepsis patients with severe respiratory failure induced by lung infection, ECMO support may improve their survival time.

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“…Although VA-ECMO can offer hemodynamic support for a cardiogenic cause of hypotension, the primary disadvantages of VA-ECMO are increased risk of stroke, bleeding, renal failure, and Harlequin syndrome (selective lower body oxygenation with upper body hypoxia) [14]. Schmid et al described the following general indications for VV-ECMO: PaO 2 /FiO 2 < 80 mmHg under FiO 2 1.0, positive end-expiratory pressure (PEEP) 18 cmH 2 O, and refractory to respiratory acidosis (pH < 7.25) despite optimized conservative therapy [15].…”

Section: Discussionmentioning

confidence: 99%

Veno-Venous Extracorporeal Membrane Oxygenation for Acute Lung Injury after Surgery for Aortic Dissection: A Case Report

Kono¹,

Oda²,

Akaiwa³

et al. 2017

WJCS

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Acute respiratory failure after surgery for aortic dissection is a serious complication that has been associated with increased mortality and morbidity. Veno-venous (VV) extracorporeal membrane oxygenation (ECMO) is reported as one of the treatments for this life-threatening complication. A 78-year-old male patient was admitted to our hospital for Stanford type A acute aortic dissection. He underwent emergency replacement of the ascending aorta, after which he developed acute lung injury. It was difficult to maintain oxygenation with a respirator mask. Therefore, VV-ECMO was initiated on postoperative day 1. The oxygenation gradually improved, and VV-ECMO was continued until postoperative day 13. On postoperative day 25, mechanical ventilation was withdrawn. The patient was discharged from the hospital on postoperative day 149. We report a case of successful treatment of acute lung injury with VV-ECMO initiated after surgery for aortic dissection. VV-ECMO can be considered as a treatment option for severe acute lung injury after surgery for aortic dissection.

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Venovenous extracorporeal membrane oxygenation for acute lung failure in adults

Cited by 92 publications

References 20 publications

Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: our single-center experience

Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: our single-center experience

Respiratory extracorporeal membrane oxygenation for severe sepsis and septic shock in adults: a propensity score analysis in a multicenter retrospective observational study

Veno-Venous Extracorporeal Membrane Oxygenation for Acute Lung Injury after Surgery for Aortic Dissection: A Case Report

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