Venous thromboembolism risk in adults with hereditary thrombophilia: a systematic review and meta-analysis
Anne B. Alnor,
Charlotte Gils,
Pernille J. Vinholt
Abstract:This systematic review and meta-analysis assesses venous thromboembolism (VTE) risk in adults with hereditary thrombophilia, including Factor V Leiden (FVL) mutation, prothrombin G20210A (FII) mutation, compound heterozygosity, protein C (PC), protein S (PS), and antithrombin (AT) deficiency. Eligibility criteria included studies suitable for quantitative synthesis with extractable information on VTE risk in adults (> 15 years). There were no restrictions on VTE type, location, or occurrence. Two authors re… Show more
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