“…For example, inpatient status, sex, anesthesia type, obesity, smoking, malignancy, operative time, CHF, COPD, anemia, and independent functional status were not associated with VTE occurrence as loosely suggested in previous literature 12, 14, 15, 33, 36, 38. However, even in recent studies, these risk factors and pre-existing conditions have not been replicated, with statistical significance often not having been met 21, 40. Many suggested mechanisms of VTE in TSA relate to procedural technique, including axillary vein damage during humeral manipulation, direct pressure from retractors, embolic showering through intramedullary reaming, lower-extremity venous stasis from beach-chair positioning, increased dissection, and prolonged operative time 4, 25, 32, 37, 42.…”