Venous Thromboembolism in Geriatric Trauma Patients—Risk Factors and Associated Outcomes

Prabhakaran, Kartik; Gogna, Shekhar; Lombardo, Gary; Latifi, Rifat

doi:10.1016/j.jss.2020.05.008

Cited by 31 publications

(36 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study also noted that a long duration of CVC intubation 42 and long endotracheal intubation 16,18 could increase symptomatic CRVT occurrence in SICU patients. In this study population, anticoagulation therapy was insu cient due to anticoagulation contraindication, and the comparison of anticoagulation therapy between the two groups was statistically signi cant (P = 0.005), which may also increase the occurrence of symptomatic CRVT.…”

Section: Discussionsupporting

confidence: 58%

See 1 more Smart Citation

Disease-Related Risk Factors for CVC-Related Symptomatic Thrombosis in Surgical ICU Inpatients

Liu

Zhu

Kuang

et al. 2020

Preprint

View full text Add to dashboard Cite

To report the rate of symptomatic catheter-related venous thrombosis (CRVT) in surgical intensive care unit patients receiving central venous catheters (CVC) and analyze the disease-related risk factors for symptomatic CRVT in SICU patients. A retrospective analysis was performed on 1643 critically ill patients admitted to the SICU from January 2015 to December 2019. Cases were divided into two groups based on the presence of symptomatic CRVT, and the variables of interest were extracted from the electronic medical record system. Logistic univariate and multivariate regression analyses were used to determine the risk factors of SCRVT. A total of 209 symptomatic CRVT events occurred among 2114 catheters. Multivariate analysis showed that trauma (odds ratio [OR], 2.046; 95% confidence interval [CI] [1.325-3.160], P = 0.001), major surgery (OR, 2.457; 95% CI [1.641-3.679], P = 0.000), and heart failure (OR, 2.087; 95% CI [1.401-3.111], P = 0.000) were independent risk factors for symptomatic CRVT in SICU. The AUROC for this model was 0.610 (95% CI [0.569-0.651], P=0.000). The incidence rate was 9.89%. For patients hospitalized in the SICU, especially those admitted with these three conditions, thromboprophylaxis and/or mechanical prophylaxis should be actively provided to reduce the occurrence of symptomatic CRVT.

show abstract

Section: Discussionsupporting

confidence: 58%

“…The traumatically injured are at an especially high risk for VTE [18][19][20][21] . In the absence of pharmacologic prophylaxis, those with severe injuries have a risk of VTE that surpasses 50% 22 .…”

Section: Discussionmentioning

confidence: 99%

Disease-Related Risk Factors for CVC-Related Symptomatic Thrombosis in Surgical ICU Inpatients

Liu

Zhu

Kuang

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…The value of the variation inflation factor (VIF) ≥3 or tolerance ≤1/3 signifies multicollinearity and thereby excludes the involved variables. 29 To address the potential for over-fitting of the logistics regression model, the Hosmer-Lemeshow test was performed, with P < 0.05 and adjusted Nagelkerke R 2 > 0.750, indicating the overfitting. 29 Odds ratio (OR) and its 95% confidential interval indicated the magnitude of association effect.…”

Section: Discussionmentioning

confidence: 99%

Relationship between surgeon volume and the risk of deep surgical site infection (DSSI) following open reduction and internal fixation of displaced intra‐articular calcaneal fracture

Qin

Zhu

Meng

et al. 2021

International Wound Journal

View full text Add to dashboard Cite

It is well established that the postoperative results were affected by the surgeon volume in a variety of elective and emergent orthopaedic surgeries; however, by far, no evidences have been available as for surgically treated displaced intra‐articular calcaneal fractures (DIACFs). We aimed at investigating the relationship between surgeon volume and deep surgical site infection (DSSI) following open reduction and internal fixation (ORIF) of DIACFs. This was a further analysis of prospectively collected data from a validated database. Patients with DIACFs stabilised by ORIF between 2016 and 2019 were identified. Surgeon volume was defined as the number of surgically treated calcaneal fractures within one calendar year and was dichotomised based on the optimal cut‐off value. The outcome measure was DSSI within 1 year postoperatively. Multivariate logistics regression analyses were performed to examine the relationship, adjusting for confounders. Among 883 patients, 19 (2.2%) were found to have a DSSI. The DSSI incidence was 6.5% in surgeons with a low volume (<6/year), 5.5 times as that in those with a high volume (≥6/year) (incidence rate, 1.2%; P < 0.001). The multivariate analyses showed a low volume <6/year was associated with a 5.8‐fold increased risk of DSSI (95% confidence interval, 2.2‐16.5, P < 0.001). This value slightly increased after multiple sensitivity analyses, with statistical significances still unchanged (OR range, 6.6‐6.9; P ≤ 0.001). The inverse relationship indicates a need for at least six cases/year for a surgeon to substantially reduce the DSSIs following the ORIF of DIACFs.

show abstract

“…Li et al confirmed that, with the increase of APACHE II score, the mortality rate gradually increases: when the score is ≥25, the mortality rate increases significantly; when the score is ≥35, the mortality rate increases to 100%. The actual mortality rate is significantly (24).…”

Section: Comparing Prophylaxis In High Vte Risk Patients With Bleeding Risk Among Elderly Icu Patientsmentioning

confidence: 99%

Venous thromboembolism risk factors and prophylaxis of elderly intensive care unit patients in a Chinese general hospital

Chen¹,

Huang²,

Liu³

et al. 2021

Ann Palliat Med

View full text Add to dashboard Cite

deaths occurring during hospitalization, especially in elderly patients. Approximately 18% to 65% of VTE-associated mortality has been reported as being preventable (2). Multimorbidity, which is defined as the co-occurrence of 2 or more chronic comorbidities is the common characteristic in the majority of elderly patients. We present the following article in accordance with the STARD reporting checklist

show abstract

Venous Thromboembolism in Geriatric Trauma Patients—Risk Factors and Associated Outcomes

Cited by 31 publications

References 16 publications

Disease-Related Risk Factors for CVC-Related Symptomatic Thrombosis in Surgical ICU Inpatients

Disease-Related Risk Factors for CVC-Related Symptomatic Thrombosis in Surgical ICU Inpatients

Relationship between surgeon volume and the risk of deep surgical site infection (DSSI) following open reduction and internal fixation of displaced intra‐articular calcaneal fracture

Venous thromboembolism risk factors and prophylaxis of elderly intensive care unit patients in a Chinese general hospital

Contact Info

Product

Resources

About