Venous Thromboembolism in Children

Sabharwal, Sanjeev; Zhao, Chen; Passanante, Marian

doi:10.1097/bpo.0b013e31829d55e3

Cited by 25 publications

(17 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Georgopoulos et al [ 8 ] used the PHIS database to calculate the incidence of VTE events associated with elective pediatric orthopaedic surgery [ 8 ]. They found a total of 71 cases over a 6-year time period within approximately 143,000 admissions, which corresponded to an incidence of 0.015 %.…”

Section: Discussionmentioning

confidence: 99%

“…Current literature regarding VTE in children with orthopaedic trauma is limited by small cohorts of patients [ 6 ] or survey responses [ 7 , 8 ]. Recently, data on VTE associated with elective orthopaedic procedures has been published [ 9 ], but there is no national data in the USA on VTE events associated with pediatric orthopaedic trauma.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Pediatric orthopaedic lower extremity trauma and venous thromboembolism

Murphy

Naqvi

Miller

et al. 2015

Journal of Children's Orthopaedics

View full text Add to dashboard Cite

PurposeResearch on venous thromboembolism events (VTE), such as deep venous thrombosis (DVT) and pulmonary embolism (PE), in pediatric orthopaedic trauma patients is sparse. We describe the incidence in the USA of VTE associated with pediatric lower extremity orthopaedic trauma, and characterize injury patterns and VTE treatment methods.MethodsThe Pediatric Health Information System (PHIS) was queried from 2004 to 2013 using ICD-9 codes for lower extremity fractures (pelvis, femur, tibia, ankle, foot) and dislocations (hip, knee, ankle, subtalar) and VTE. Records were queried for age, diagnoses, and VTE treatment.ResultsDuring the study period 285,611 clinical encounters reported lower extremity trauma. Of those, 167 patients were simultaneously coded with VTE (99 DVT, 50 PE, 18 combined DVT/PE), to give an incidence of VTE associated with pediatric lower extremity trauma of 0.058 %. Patients were from 39 centers, with an average age of 12.9 years (range 0–19). There were 249 fractures and 21 dislocations, with 25 (15 %) patients sustaining more than one lower extremity injury. The most common fracture locations were the femur/femoral neck (95), tibia/ankle (92), and pelvis (44). 72 % (121/167) of patients were treated with anticoagulation medication, of which the most common was low-molecular-weight heparin (111/167, 66 %).ConclusionsThe incidence of VTE events associated with lower extremity orthopaedic trauma is 0.058 %. Adolescents and polytrauma patients with injuries of the femur/femoral neck, tibia/ankle, and pelvis are more commonly affected. Low-molecular-weight heparin is commonly used to treat VTE in pediatric and adolescent patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Pediatric orthopaedic lower extremity trauma and venous thromboembolism

Murphy

Naqvi

Miller

et al. 2015

Journal of Children's Orthopaedics

View full text Add to dashboard Cite

show abstract

“…Sabharwal et al reported on a follow-up web-based questionnaire from members of the Pediatric Orthopedic Society of North America looking at VTE following nonspecific surgery in pediatrics [ 3 ]. Results extrapolated from 46 children revealed that the most commonly cited predisposing factors for the development of VTE were having undergone lower extremity surgery and being an adolescent.…”

Section: Discussionmentioning

confidence: 99%

Symptomatic bilateral pulmonary embolism without deep venous thrombosis in an adolescent following arthroscopic anterior cruciate ligament reconstruction: a case report and review of the literature

et al. 2018

View full text Add to dashboard Cite

BackgroundVenous thromboembolism, specifically pulmonary embolism, is a rare complication following elective pediatric orthopedic surgery. Bilateral pulmonary embolism with associated pulmonary hemorrhage/infarct without concomitant deep vein thrombosis has never been reported following routine anterior cruciate ligament reconstruction in an adolescent.Case presentationA 16-year-old white girl presented with acute onset shortness of breath and pleuritic chest pain 6 days following elective anterior cruciate ligament reconstruction. After performing a thorough work-up, she was diagnosed as having provoked bilateral pulmonary embolism with associated pulmonary hemorrhage without concomitant deep vein thrombosis. She was treated successfully with 3 months of anticoagulation therapy with daily Lovenox (enoxaparin) injections.ConclusionsSymptomatic bilateral pulmonary embolism may have a good prognosis if it is diagnosed early and treated appropriately. It is important to appreciate the risk of provoked thromboembolic events in healthy adolescents undergoing arthroscopic knee surgery.

show abstract

“…An article by Sabharwal and coauthors [ 4 ] surveying members of the Pediatric Orthopaedic Society of North America is the seventh reference in the reference list at the end of the paper but is cited in the text as the fifth reference in the list. The follow-up survey by Sabharwal et al [ 5 ] is given as the eighth reference in the list, but is cited as the sixth. Finally, the last sentence of the fourth paragraph of the “Discussion” reports a survey by Sabharwal et al [ 4 ] on using low-molecular-weight heparin to treat VTE; this is the seventh reference in the list but is cited as the ninth.…”

mentioning

confidence: 99%