Venous oximetry

Marx, Gernot; Reinhart, Konrad

doi:10.1097/01.ccx.0000224872.09077.dc

Cited by 115 publications

(89 citation statements)

References 40 publications

(35 reference statements)

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“…This led to no apparent measurement different and lead to the finding that both treatments induced increased SvO 2 levels relative to baseline at all-time points, indicating an improvement in cardiovascular performance. [10][11][12] This effect was confirmed by the cardiac index measurements in the GDT patients, monitored through the pulmonary artery catheter.…”

Section: ■ Discussionmentioning

confidence: 55%

Goal-directed therapy for decompensated heart failure and renal dysfunction. A pilot randomized clinical trial

Bastos¹,

Ferri²,

Lima³

et al. 2016

Medical Express

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OBJECTIVES:Acute heart failure is associated with low cardiac output syndrome and renal dysfunction. However, it is not known whether a goal-directed protocol guided by tightly controlled hemodynamic variables, including pulmonary artery catheter, will safely improve clinical renal dysfunction markers in these patients when compared to a less invasive approach. METHODS: Pilot, randomized clinical trial aimed at patients with known heart failure, low cardiac output syndrome and renal dysfunction with less than 48 hours from onset. We randomized two groups: (a) goal-directed therapy monitored with pulmonary artery catheter and (b) conventional therapy with central venous catheter. Hemodynamic parameters, venous oxygen saturation, serum lactate, fluid repositions and vasoactive drugs were compared considering renal function improvement after 72 hours as the primary study endpoint. We included 15 goal-directed therapy and 16 conventional therapy patients. The study has assessed patients on baseline looking for significant improvement at 72 hours of the following parameters in the goal-directed therapy and conventional therapy groups: urine output, serum creatinine, venous oxygen saturation and serum lactate. RESULTS: Baseline characteristics were similar in both groups. In the first 24 hours there was a lower volume of fluid reposition in the goal-directed therapy group, although 72 hours later such reposition was equivalent. The use of inotropic agents was similar between groups. There was an improvement to the renal function and the hemodynamic parameter in both study groups. CONCLUSIONS: The option for the protocol with pulmonary artery catheter setting is justified only if there is clinical evidence of serious pulmonary congestion associated to low peripheral perfusion.

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Section: ■ Discussionmentioning

confidence: 55%

Goal-directed therapy for decompensated heart failure and renal dysfunction. A pilot randomized clinical trial

Bastos¹,

Ferri²,

Lima³

et al. 2016

Medical Express

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“…Increased venous oxygen saturation is thought to be an indicator for reduced oxygen utilization as well as arteriovenous shunting. 29 In normal human physiological conditions, the oxygen saturation of the veins draining their respective organs within the body is highly variable which is thought to reflect variations in the oxygen extraction levels or metabolic activity of the tissues. 30 This is most evident in the renal venules whose oxygen saturation is approximately 92% as a result of relatively low-oxygen extraction in the renal tissues which derives its energy requirements from non-oxidative phosphorylation.…”

Section: Discussionmentioning

confidence: 99%

Oxygen saturation measurements of the retinal vasculature in treated asymmetrical primary open-angle glaucoma using hyperspectral imaging

Mordant

Alabboud

Muyo

et al. 2014

Eye

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Purpose To determine whether there are differences in retinal vascular oxygen saturation measurements, estimated using a hyperspectral fundus camera, between normal eyes and treated eyes of subjects with asymmetrical primary open-angle glaucoma (POAG). Methods A noninvasive hyperspectral fundus camera was used to acquire spectral images of the retina at wavelengths between 556 and 650 nm in 2-nm increments. In total, 14 normal eyes and both eyes of 11 treated POAG subjects were imaged and analyzed using algorithms that use the spectral variation of the optical densities of blood vessels to estimate the oxygen saturation of blood within the retinal vasculature. In the treated POAG group, each of the eyes were categorized, based on the mean deviation of the Humphrey visual-field analyzer result, as either more-advanced or less-advanced, glaucomatous eyes. Unpaired t-tests (twotailed) with Welch's correction were used to compare the mean oxygen saturation between the normal subjects and the treated POAG subgroups. Results In less-advanced and moreadvanced-treated POAG eyes, mean retinal venular oxygen saturations (48.2 ± 21.6% and 42.6 ± 18.8%, respectively) were significantly higher than in normal eyes (27.9 ± 9.9%; P ¼ 0.03 and 0.01, respectively). Arteriolar oxygen saturation was not significantly different between normal eyes and treated POAG eyes. ConclusionsThe increased oxygen saturation of the retinal venules in advancedtreated POAG eyes may indicate reduced metabolic consumption of oxygen in the inner retinal tissues.

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“…Many studies have shown that in the early stages of resuscitation of patients with septic shock, a decrease in ScvO 2 is an important manifestation of inadequate tissue perfusion (Marx and Reinhart, 2006). In a retrospective study on the performance of the international guidelines for septic shock treatment (Levy et al, 2010), Levy reported that the hospital mortality in patients with septic shock had decreased from 37 to 30.8% after 3 years of implementation of the guidelines.…”

Section: Discussionmentioning

confidence: 99%

Monitoring tissue blood oxygen saturation in the internal jugular venous area using near infrared spectroscopy

Ruan

Ren

et al. 2015

Genet. Mol. Res.

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ABSTRACT. Central venous blood oxygen saturation (ScvO 2 ) is an important monitoring index of fluid resuscitation. However, monitoring of ScvO 2 is not continuous and invasive. Near infrared spectroscopy (NIRS) is an optical technology for the noninvasive detection of hemodynamic changes, with advantages of being real-time, continuous, low-cost, and portable. The present study aimed to determine whether a correlation exists between the tissue blood oxygen saturation in the internal jugular venous area (StO 2 ) data obtained with NIRS and the ScvO 2 and whether these two quantities are equivalent. Data were collected from 13 patients. We used ultrasound to locate the placement site for the NIRS light source outside the internal jugular vein. Meanwhile, a sample for blood gas analysis was obtained through the Monitoring tissue blood oxygen saturation central venous catheter. A correlation analysis between the StO 2 and ScvO 2 of 13 samples was performed (Pearson correlation coefficient), suggesting a high correlation between them (r = 0.906, StO 2 =1.0018 ScvO 2 +2.8524). Bland-Altman analysis was also performed between the StO 2 and ScvO 2 . Results were as follows: 100% of monitored points fell within the range of the mean ± 1.96 SD of the difference between the StO 2 and ScvO 2 ; range of the mean ± 1.96 SD of the difference between the StO 2 and ScvO 2 was 3 ± 10.2; confidence interval of the difference between the StO 2 and ScvO 2 was -7.2 to 13.2%. The StO 2 monitored with NIRS correlated highly with the ScvO 2 measured in the internal jugular vein. Therefore, the StO 2 can be used for directing clinical treatment with further research.

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Venous oximetry

Cited by 115 publications

References 40 publications

Goal-directed therapy for decompensated heart failure and renal dysfunction. A pilot randomized clinical trial

Goal-directed therapy for decompensated heart failure and renal dysfunction. A pilot randomized clinical trial

Oxygen saturation measurements of the retinal vasculature in treated asymmetrical primary open-angle glaucoma using hyperspectral imaging

Monitoring tissue blood oxygen saturation in the internal jugular venous area using near infrared spectroscopy

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