Venous-Compression Test in Hyperparathyroidism

Laboratory Tests in the Differentiation of Hyperparathyroidism from other Causes of Hypercalcaemia

“…Recently it has been reported that venous compression of the arm (100 mmHg) with rhythmical fist-clenching for 15 min. in hyperparathyroid patients caused a substantial rise in plasma calcium concentration in that arm, when compared with normal subjects (Krull, Muller, Leijnse, and Gerbrandy, 1969). It was proposed that this effect was associated with local acidosis augmenting the skeletal release of calcium in the hyperparathyroid patients, this explanation hardly seems tenable as the authors state that there was no rise in plasma phosphorus concentration.…”