Venous Allografts Preserved at 4°C for Infrainguinal Bypass: Long-Term Results from 170 Procedures

Outcomes of cold-stored venous allograft for below-knee bypasses in patients with critical limb ischemia

“…Currently, only six studies have reported the use of venous allografts preserved at 4 C for infrainguinal bypasses [11][12][13][14][15][16] (Table IX). Our experience is the first evaluating cold-stored venous allograft only supplied by BioProtec and reporting outcomes according to the OPGs of the SVS for CLI.…”

“…Cold-stored venous allografts can be an alternative to cryopreservation. [11][12][13][14][15][16] In our institution, since 2002, we have used cold-stored venous allografts obtained from ablation of varicose GSVs. The aim of this study was to assess our long-term results of below-knee revascularizations using a cold-stored venous allograft in patients with CLI.…”

Die homologe Venentransplantation zur kruropedalen arteriellen Rekonstruktion

“…Wir haben nur solche Patienten transplantiert, die ohne diese Operation mit an Sicherheit grenzender Wahrscheinlichkeit ihr Bein kurzfristig verloren hätten (Amputationsindikation).Die akute komplette Ischämie stellt derzeit keine Indikation zur homologen VTx dar,weil die Spendergefäße nicht vorrätig sind. Hier kön-nen Kryopreservate eine vorübergehen-de Abhilfe sein [1], wenngleich auch hier die sekundäre Offenheitsrate infrapoplitealer Eingriffe von Streinchenberger et al mit nur 30% angegeben wird [21], mit einer Immunsuppression (Azathioprin) können von Carpenter und Tomaszewski nach einem Jahr nur noch 18% eine primäre Offenheit vorweisen [3].…”

Acute Humoral Rejection in Kidney Allograft Following a Third-Party Arterial Transplantation

“…The success of allogeneic vessel transplantation may be due to minimal immunogenicity, and to the repopulation of endothelial walls by recipient cells (1,2). According to some reports, these allografts are subject to frequent and early failure, presumably due to local injury, hypercoagulability but also due to alloimmune rejection.…”

“…Patients with peripheral arterial occlusion benefit from allogeneic vessel grafts (1). However, frequently after such surgical procedures anti-HLA antibodies develop, but their pathogenicity remains controversial.…”