Vehiculation of Methyl Salicylate from Microcapsules Supported on Textile Matrix

Abstract

In recent years, textile industries have focused their attention on the development of functional finishing that presents durability and, consequently, controlled release. However, in the case of methyl salicylate microcapsules supported on a textile matrix, studies indicate only the interactions between substrate and microcapsules and the drug delivery system, not applying the release equations. This study reports the mechanism and kinetics of controlled release of microcapsules of gelatin and gum Arabic containing methyl salicylate as active ingredient incorporated into textile matrices. According to the results presented, it was possible to verify that the wall materials participated in the coacervation process, resulting in microcapsules with well-defined geometry, besides promoting the increase of the thermal stability of the active principle. The samples (100% cotton, CO, and 100% polyamide, PA) functionalized with microcapsules released methyl salicylate in a controlled manner, based on the adjustment made by the Korsmeyer–Peppas model, indicating a Fickian mechanism. The influence of temperature was noticeable when the samples were subjected to washing, since with higher temperature (50 °C), the release was more pronounced than when subjected to lower temperature (37 °C). The results presented in this study indicate that the mechanism of backbone release is influenced by the textile matrix and by the durability of the microcapsule during the wash cycles.

Microencapsulation for Functional Textile Coatings with Emphasis on Biodegradability—A Systematic Review

“…Microcapsules must be composed of natural and biocompatible materials and approved for direct skin contact. Examples of medical textiles include microencapsulated antibiotics [76], methyl salicylate [77], cannabidiol [78], ozonated vegetable oils [79], lime oil [80] and chitosan [81]. Microcapsules for cosmetotextiles [82] contain skin-caring active ingredients, such as essential oils and vitamins [83][84][85].…”

“…The durability of the microcapsules and the maintenance of the functionality of the textile during its lifetime depend on the resistance of the binder layer to washing, dry and wet cleaning, rubbing and light. It should be emphasised that all washfastness properties in textiles are standardised by the standards ISO 105-C01 [131,139], ISO 105-C10 [141], ISO 105-C06, ISO 6330 or AATCC TM61 [77,89,121,136,145]. The standard ISO 105-C01 is no longer valid anymore and is replaced by ISO 105-C10.…”

Reservoir Effect of Textile Substrates on the Delivery of Essential Oils Microencapsulated by Complex Coacervation

“…As a result, textiles have gained increased attention and more functions than clothing. Therefore, textiles can be used as drug carriers, which means they can be vehicles for the controlled release of pharmaceutical agents [ 1 ].…”

Functionalized Polyethylene Glycol as a Catalyst for Esterification of Salicylic Acid

“…Methyl salicylate is an ingredient of wintergreen and other plants like Amblyomma veriegatum, and it's utilized as a local anesthetic and disinfectant in toothpaste, mouthwash, fragrances, and flavoring agents. Methyl salicylate is utilized for a variety of medical purposes, including the treatment of muscle discomfort [2]. Former researchers have demonstrated the use of homogeneous and heterogeneous catalysts.…”