Vegetable Oil–Based Pickering Nanoemulsions As Carriers for Cytosolic Drug Delivery
Rajkumar Sahoo,
Nayana Mukherjee,
Sanchita Paramanik
et al.
Abstract:Pickering emulsions are attractive carriers and platforms in the cosmetic, food, and biomedical industries. However, their application as delivery carriers is restricted due to their larger size and premature cargo release. Here, we show that Pickering nanoemulsion of 200−300 nm size can be used as drug delivery carriers by a nonendocytic approach via the fusion of oil droplets with cell membranes. We found that this unique delivery feature offers enhanced cytosolic delivery of camptothecin along with predomin… Show more
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