Vector Competence of Ixodes scapularis and Ixodes ricinus (Acari: Ixodidae) for Three Genospecies of Borrelia burgdorferi

Mc, Dolan; Piesman, Joseph; Ml, Mbow; Go, Maupin; Péter, Olivier; Brossard, Michel; Wt, Golde

doi:10.1093/jmedent/35.4.465

Cited by 39 publications

(25 citation statements)

References 29 publications

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“…genospecies such as western fence lizards (S. occidentalis) that are refractory to B. burgdorferi (Kurtenbach et al, 2002b). Similarly, there is evidence that compatibility and transmission efficiency can also vary with vector-pathogen associations (Dolan et al, 1998). Particular B. burgdorferi s.s. outer surface protein C (OspC) or rrs-rrl genotypes that are found only in certain vertebrate hosts may reflect the presence of host-specific pathogen compatibility as well (Brisson, 2004;Girard et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

Comparative genetic diversity of Lyme disease bacteria in Northern Californian ticks and their vertebrate hosts

Swei

Bowie

2015

Ticks and Tick-borne Diseases

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Section: Discussionmentioning

confidence: 99%

Comparative genetic diversity of Lyme disease bacteria in Northern Californian ticks and their vertebrate hosts

Swei

Bowie

2015

Ticks and Tick-borne Diseases

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“…On the West Coast of the United States, the primary vector is a morphologically similar species, Ixodes pacificus (107,163,164). In Europe, including the British Isles, I. ricinus is the primary vector for LD, HA, and probably babesiosis (43,56,68,71,77,188,208), but it is largely replaced by I. persulcatus in Eastern Europe and Asia (6,37,203).…”

Section: Biology and Ecology Of Ixodes Ticksmentioning

confidence: 99%

Coinfections Acquired from Ixodes Ticks

et al. 2006

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SUMMARY The pathogens that cause Lyme disease (LD), human anaplasmosis, and babesiosis can coexist in Ixodes ticks and cause human coinfections. Although the risk of human coinfection differs by geographic location, the true prevalence of coinfecting pathogens among Ixodes ticks remains largely unknown for the majority of geographic locations. The prevalence of dually infected Ixodes ticks appears highest among ticks from regions of North America and Europe where LD is endemic, with reported prevalences of ≤28%. In North America and Europe, the majority of tick-borne coinfections occur among humans with diagnosed LD. Humans coinfected with LD and babesiosis appear to have more intense, prolonged symptoms than those with LD alone. Coinfected persons can also manifest diverse, influenza-like symptoms, and abnormal laboratory test results are frequently observed. Coinfecting pathogens might alter the efficiency of transmission, cause cooperative or competitive pathogen interactions, and alter disease severity among hosts. No prospective studies to assess the immunologic effects of coinfection among humans have been conducted, but animal models demonstrate that certain coinfections can modulate the immune response. Clinicians should consider the likelihood of coinfection when pursuing laboratory testing or selecting therapy for patients with tick-borne illness.

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“…The principal vectors of B. burgdorferi sensu lato are ticks of the Ixodes ricinus complex (2). Two tick species, I. ricinus and Ixodes persulcatus, are present in Latvia, and vector competence for these two species has been experimentally confirmed (3,5,8,10,24,28). Identification of the pathogenic B. burgdorferi species in ticks has epidemiological importance, since they are prime factors in determining the risk of acquiring LB and its clinical presentation.…”

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confidence: 99%

Identification of Three Clinically Relevant Borrelia burgdorferi Sensu Lato Genospecies by PCR-Restriction Fragment Length Polymorphism Analysis of 16S-23S Ribosomal DNA Spacer Amplicons

et al. 2004

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We report the results of a study of the prevalences of three clinically relevant Borrelia burgdorferi sensu lato genospecies (Borrelia burgdorferi sensu stricto, Borrelia afzelii, and Borrelia garinii) in 1,040 questing Ixodes ticks from all regions of Latvia, where Lyme borreliosis is endemic. The prevalences of Borrelia in Ixodes ricinus and Ixodes persulcatus were 22.6 and 27.9%, respectively. Molecular typing of B. burgdorferi from infected ticks was performed by restriction fragment length polymorphism (RFLP) analysis of PCR-amplified fragments of the 16S-23S (rrs-rrlA) rRNA intergenic spacer by using species-specific primers and subsequent sequencing. The dominant Borrelia species in both Ixodes species was B. afzelii. In addition, different restriction patterns of B. garinii and B. afzelii were also identified. This study demonstrates that the 16S-23S rRNA PCR-RFLP typing method is simple, sensitive, and fast and that it allows one to differentiate among B. burgdorferi species and subspecies with various degrees of pathogenic potential directly in ticks. These features are important in monitoring Lyme disease.

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Vector Competence of Ixodes scapularis and Ixodes ricinus (Acari: Ixodidae) for Three Genospecies of Borrelia burgdorferi

Cited by 39 publications

References 29 publications

Comparative genetic diversity of Lyme disease bacteria in Northern Californian ticks and their vertebrate hosts

Comparative genetic diversity of Lyme disease bacteria in Northern Californian ticks and their vertebrate hosts

Coinfections Acquired from Ixodes Ticks

Identification of Three Clinically Relevant Borrelia burgdorferi Sensu Lato Genospecies by PCR-Restriction Fragment Length Polymorphism Analysis of 16S-23S Ribosomal DNA Spacer Amplicons

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