Vector and Host Relationships of California Serogroup Viruses in Western Siberia

Mitchell, Carl J.; L'vov, S D; Savage, Harry M.; Calisher, Charles H.; Smith, Gordon Cs; Львов, Д К; Gubler, Duane J.

doi:10.4269/ajtmh.1993.49.53

Cited by 21 publications

(18 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…mosquitoes collected from the Kalinin region. [10][11][12] The areas also differ ecologically. Whether these isolates, as a group or as individuals, should be considered new viruses remains to be determined.…”

Section: Discussionmentioning

confidence: 99%

“…9 During epidemiologic studies to identify the CAL serogroup viruses associated with the severe CNS infections, numerous CAL serogroup viruses were isolated from mosquitoes, including 83 isolates of SSH virus, 44 isolates of INK virus, and 2 isolates of TAH virus. [10][11][12] Most of the isolates were identified by hemagglutination (HI) and plaque reduction neutralization (N) tests to be SSH, INK, or TAH virus; however, some of the isolates from mosquito in Russia (e.g., LEIV-11483, LEIV-11554, LEIV-18373, and LEIV-12812) and isolates from patients (e.g., LEIV-27044) could not be unequivocally identified as SSH or TAH virus by the HI and N tests. 11 Western blot analyses of the polymerase protein suggested that certain viruses were reassortants (Lvov D, unpublished data).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Molecular characterization of California serogroup viruses isolated in Russia.

Vanlandingham¹,

Davis²,

Львов³

et al. 2002

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Molecular characterization of California serogroup viruses isolated in Russia.

Vanlandingham¹,

Davis²,

Львов³

et al. 2002

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

“…The European hare (Lepus europaeus) is considered a major reservoir host for TAHV (Simkova 1963, Aspöck andKunz 1971); however, high seroprevalence rates of anti-TAHV immunoglobulin G (IgG) antibodies were also identified in small mammals and insectivores (Málková et al 1969, Le Lay-Rogues et al 1984, Mitchell et al 1993 as well as in mediumsized and large mammals , Madić et al 1993) and birds , Juricová et al 1998, suggesting a wide range of vertebrate reservoir species.…”

Section: Introductionmentioning

confidence: 97%

“…INKV is widespread in Northern Europe and has been isolated from Aedes communis in Sweden (Francy et al 1989), from A. hexodontus and A. punctor in Russia (Mitchell et al 1993) and it is also quite common in Finland (BrummerKorvenkontio and Saikku 1975).…”

Section: Introductionmentioning

confidence: 99%

Investigations on California Serogroup Orthobunyaviruses in the Tyrols: First Description of Tahyna Virus in The Alps

Sonnleitner

Lundström

Baumgartner

et al. 2014

Vector-Borne and Zoonotic Diseases

View full text Add to dashboard Cite

Seroprevalence rates for immunoglobulin G (IgG) antibodies to Tahyna virus (TAHV) and Inkoo virus (INKV) were determined in sera of 1630 blood donors from North, East, and South Tyrol by immunofluorescence assays (IFAs) and confirmatory serum neutralization tests (SNTs). Ten sera (0.6%) reacted positive by TAHV IFA, five of which (0.3%) were confirmed by SNT. Eleven sera (0.7%) reacted positive in the INKV IFA; only one thereof (0.06%) was verified by subsequent SNT. To identify the source of infections, mosquitoes were trapped at 18 sampling sites in the study area, resulting in the collection of 2571 adult mosquitoes: 1254 individuals of the genus Aedes (48.8% of total) including A. albopictus, 640 Culex (24.9%), 303 Coquillettidia (11.8%), 252 Ochlerotatus (9.8%), 49 Anopheles (1.9%), and 73 mosquitoes of the genus Culiseta (2.8%). The mosquitoes were pooled according to species, trapping site, and time, and were tested by RT-PCR for the presence of California serogroup orthobunyavirus nucleic acids. PCR amplification products were obtained in five of 195 pools (2.6%), and all were identified as TAHVs by subsequent sequencing. This represents the first evidence of TAHV circulation and human exposure in the Tyrols and in the alpine region in general. Interestingly, all TAHV sequences were identified in Culex pipiens/torrentium mosquitoes. Whether other California serogroup orthobunyaviruses such as INKV are also circulating in this area is subject of further investigations on larger numbers of mosquitoes.

show abstract

“…Snowshoe Hare virus (SSHV), Inkoo virus (INKV), TAHV, and Batai virus (BATV), originally isolated in the United States (14), Finland (30), the Czech Republic (3), and Slovakia (2), respectively, have all been isolated in Siberia (20)(21)(22). TAHV and BATV have been isolated in several Western European countries (19), and the isolation of BATV has also been reported in Sudan (24) and India (12).…”

mentioning

confidence: 99%

Rapid Detection of Human Pathogenic Orthobunyaviruses

et al. 2003

View full text Add to dashboard Cite

Modern detection and identification tools can help to provide answers to urgent questions about the incidence, prevalence, and epidemiology of currently emerging diseases. We developed highly sensitive one-step TaqMan reverse transcription-PCR assays with sensitivities ranging from 10 4 to 10 1 molecules for 11 human pathogens of the orthobunyaviruses. We compared the performances of these assays on three currently available cyclers (ABI-PRISM 7700, LightCycler, and SmartCycler). The assay for Oropouche virus (OROV) was tested using sera collected from days 1 to 5 after onset of OROV disease and was found to be greatly superior to an established nested PCR system. A mean copy number of 1.31 ؋ 10 7 OROV RNA/ml of serum was detected. Diagnostic RNA detection can be used as early as day 1 after onset of OROV disease. The use of a mobile SmartCycler and a hands-on time of less than 3 h could help to intensify outbreak surveillance and control, especially in field studies.

show abstract

Vector and Host Relationships of California Serogroup Viruses in Western Siberia

Cited by 21 publications

References 0 publications

Molecular characterization of California serogroup viruses isolated in Russia.

Molecular characterization of California serogroup viruses isolated in Russia.

Investigations on California Serogroup Orthobunyaviruses in the Tyrols: First Description of Tahyna Virus in The Alps

Rapid Detection of Human Pathogenic Orthobunyaviruses

Contact Info

Product

Resources

About