VaxSeer: Selecting influenza vaccines through evolutionary and antigenicity models
Wenxian Shi,
Jeremy Wohlwend,
Menghua Wu
et al.
Abstract:Even though vaccines have the potential to significantly alleviate the disease burden of epidemics such as the seasonal flu, current influenza vaccines offer limited protection. According to the Centers for Disease Control and Prevention (CDC), vaccine effectiveness has hovered below 50% for the past decade. Identifying the optimal strains to use in a vaccine is central to increasing its efficacy. However, this task is challenging due to the antigenic drift that occurs during the flu season. In this paper, we … Show more
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