Journal of Cell Biology volume 217, issue 4, P1503-1519 2018 DOI: 10.1083/jcb.201702048 View full text
|
|
Share
Hebatullah Laban, Andreas Weigert, Joana Zink, Amro Elgheznawy, Christoph Schürmann, Lea Günther, Randa Abdel Malik, Sabrina Bothur, Susanne Wingert, Rolf Bremer, Michael A. Rieger, Bernhard Brüne, Ralf P. Brandes, Ingrid Fleming et al.

Abstract: In ischemic vascular diseases, leukocyte recruitment and polarization are crucial for revascularization and tissue repair. The study of Laban et al. provides evidence that VASP is a major regulator of leukocyte recruitment and polarization and vascular repair after ischemia. Mechanistically, the study supports a novel role of VASP in chemokine receptor trafficking.