Vasovagal Reaction and Ischemic Colitis Following Blood Donation

Abstract

Vasovagal reactions are the most common type of adverse reaction after blood donation; however, there are no reports of ischemic colitis as an adverse reaction after blood donation.A previously healthy 55-year-old woman suffered loss of consciousness at the end of her first plasma donation. She was diagnosed with a vasovagal reaction and received hydration. However, she developed persistent left flank pain and watery diarrhea, followed by bloody diarrhea. Abdominal computed tomography confirmed ischemic colitis. She was asked to fast and was eventually discharged 7 days later.We should consider the possibility of ischemic colitis if patients develop persistent abdominal pain after transient hypotension, such as that observed during a vasovagal reaction.

Case report: Malignant vasovagal reflex syndrome during percutaneous transcatheter closure of patent foramen ovale

“…VVRS is not uncommon during cardiac interventional procedures, but this does not mean that it should be neglected. VVRS has also been reported after venipuncture or even vaccination ( 13 , 14 ). This indicates that VVRS is not confined to the heart but is present throughout the circulation system.…”

Reply to "Detailed Pathophysiology of Ischemic Colitis Following Plasma Donation"

“…Naoto Mizumura 1 , Takuma Kishimoto 2 , Tomoki Tanaka 1 , Junji Shimizu 1 , Takahisa Tabata 1 and Yutaka Eguchi 1…”

“…The Authors Reply We would like to thank Dr. Izumida and Dr. Imamura for their interest in our paper (1) and for taking the time to express their concerns. Their concerns were "whether such a transient (only 10 seconds) colonic hypo-perfusion would cause ischemic colitis" and whether "thrombophilia (i.e., a deficiency of protein C, protein S, and anti-thrombin III) might be associated with ischemic colitis"…”

Detailed Pathophysiology of Ischemic Colitis Following Plasma Donation

“…To the Editor We have read with great interest a case report written by Mizumura et al (1), showing that the lack of a transient colonic blood supply might be a key factor in the onset of ischemic colitis. Two concerns should improve the quality of their report.…”