“…Independent of their various concepts (col[agen plug, intra-arterial anchor/collagen combination, thrombin/collagen procoagulant or vascular suture), all sealing devices have shown to significantly reduce time to hemostasis [1,2,8,12,14,[17][18][19][20][21]25]. Independent of their various concepts (col[agen plug, intra-arterial anchor/collagen combination, thrombin/collagen procoagulant or vascular suture), all sealing devices have shown to significantly reduce time to hemostasis [1,2,8,12,14,[17][18][19][20][21]25].…”