Vasodilators in Peripheral Vascular Disease

Intra-arterial Therapy in Occlusive Vascular Disease

“…Indeed, Wilson and Quash (1951), studying the effects of tolazoline, also came to the conclusion that it was valuable in the treatment of refractory leg ulcers. It is worthy of note that Douthwaite and Finnegan (1950) were impressed by the results of oral tolazoline in patients with intermittent claudication.…”

Priscol in Treatment of Peripheral Vascular Disease

“…He noted that the blood pressure may increase. Douthwaite and Finnegan (1950) found priscol to have a more lasting vasodilator effect than the commonly used vasodilators, and noted a selective affinity for the smaller arteries of the hands and toes. In nine patients with Raynaud's disease they obtained excellent results, and produced improvement in 24 patients who had claudication of arteriosclerotic origin.…”