2004
DOI: 10.1055/s-2004-818352
|View full text |Cite
|
Sign up to set email alerts
|

Vasoaktives Intestinales Polypeptid (VIP) im Atemtrakt: Physiologie und Pathophysiologie

Abstract: ZusammenfassungDurch die Charakterisierung verschiedenster pulmonaler Effekte gewannen peptiderge Neuromediatoren in den letzten Jahren zunehmend an Bedeutung für das Verständnis physiologischer und pathophysiologischer Mechanismen im Atemtrakt. Dabei spielt Vasoaktives Intestinales Polypeptid (VIP) eine besondere Rolle aufgrund seiner potenziell anti-inflammatorischen und immunmodulierenden Wirkung. Es wird neurophysiologisch zu den Mediatoren des inhibierenden nicht-adrenergen nicht-cholinergen Nervensystems… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

0
3
0
1

Year Published

2006
2006
2016
2016

Publication Types

Select...
7

Relationship

0
7

Authors

Journals

citations
Cited by 8 publications
(4 citation statements)
references
References 71 publications
0
3
0
1
Order By: Relevance
“…The possibility to functionally assess the secretory activity under defined experimental conditions offers the chance to study the effects of potential new compounds on airway secretion in COPD. Also, the effects of mediators of inflammation including reactive oxygen species [ 61 ] or neuromediators [ 62 , 63 ] and drug transport mechanisms [ 64 , 65 ] can be assessed in a setting of phlegm production and bronchitis.…”
Section: Discussionmentioning
confidence: 99%
“…The possibility to functionally assess the secretory activity under defined experimental conditions offers the chance to study the effects of potential new compounds on airway secretion in COPD. Also, the effects of mediators of inflammation including reactive oxygen species [ 61 ] or neuromediators [ 62 , 63 ] and drug transport mechanisms [ 64 , 65 ] can be assessed in a setting of phlegm production and bronchitis.…”
Section: Discussionmentioning
confidence: 99%
“…Vasoactive intestinal peptide (VIP), a gastrointestinal hormone in the secretin–VIP family, was discovered by Said and Mutt in 1970 1 and has extensive physiological functions involving various activities of the digestive, respiratory, circulating, urogenital, and nervous systems 2,3 . The physiological functions of VIP in the gastrointestinal tract are associated with secretory and digestive motor functions 4 .…”
Section: Introductionmentioning
confidence: 99%
“…The physiological functions of VIP in the gastrointestinal tract are associated with secretory and digestive motor functions 4 . VIP exerts its actions by binding to specific membrane receptors (VIPR 1 , VIPR 2 ) 2–4 . VIPR are G protein‐coupled receptors, which are distributed in most human tissues 5–7 .…”
Section: Introductionmentioning
confidence: 99%
“…Die Hauptwirkungen in den Atemwegen sind vaso-und bronchodilatatorische Effekte bzw. eine Steigerung der glandulären Sekretion[11,20,32,33]. Unter physiologischen Bedingungen werden die parasympathischen Reaktionen als nasale Schutz-und Reinigungsmechanismen (z.…”
unclassified