Abstract:SUMMARYThe metabolic activity of frog lung perfused through its vascular bed has been assessed by determining changes in metabolites in the perfusion medium and by measuring the adenine nucleotides, ions and water in the tissue after perfusion under a variety of conditions. The addition of respiratory inhibitors, CN-or antimycin A, reduced the adenylate energy charge when a glucose-free perfusate was used but not when glucose was present. CN-and anaerobiosis stimulated lactate production while iodoacetate redu… Show more
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