Vascularization of Conjunctival Autografts in Pterygium Surgery: Comparison of Fibrin Glue with Sutures

Küçükerdönmez, Cem; Karalezlı, Aylin; Zengin, Mehmet Özgür; Akova, Yonca A.

doi:10.5301/ejo.5000466

Cited by 8 publications

(5 citation statements)

References 27 publications

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“…In this study, we evaluated the influence of pterygium removal accompanied by autologous conjunctival autografts and the use of human fibrin tissue glue on changes in corneal parameters, as measured by 3-D swept-source AS-OCT imaging. The superiority of the sutureless method in terms of shorter surgery duration and improvement of patient's comfort in postoperative period without negative impact on complications rate has been well documented [9][10][11][12][13][14]. The location of the pterygium as a superficial corneal lesion determines its alterations of corneal topography.…”

Section: Discussionmentioning

confidence: 99%

Effect of Pterygium Removal Combined with Conjunctival Autograft on Corneal Parameters in Swept-Source Imaging

Wiącek

Kuśmierz-Wojtasik

Kowalska

et al. 2022

JCM

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Background: Both pterygium ingrowth and excision determine alterations in corneal topography. The aim of this study was to evaluate the influence of pterygium removal combined with conjunctival autografts in addition to the use of human fibrin tissue glue on changes in corneal parameters as measured by 3-D swept-source anterior segment optical coherence tomography (AS-OCT) imaging. Methods: Sixteen eyes (16 patients) with pterygium that qualified for surgical treatment were enrolled in this study. Eye examination, slit lamp, and 3-D AS-OCT (CASIA 2) assessment were performed before the surgery and 7 days, 1 month, and 6 months after pterygium excision. Topographic parameters of both anterior and posterior surfaces of the cornea were analysed at each follow-up visit. Results: The gradual decrease in total astigmatism power from preoperative median 2.75 (6.15) D to 1.2 (1.1) D at 6-month follow-up (p = 0.034) was noted from the day 7 visit. Values were strongly influenced by variations of anterior cornea astigmatism. In contrast, a gradual total HOA reduction at the 1-month (from median 0.79 (1.3) D to 0.44 (0.27) D; p = 0.038) and at 6-month visits (0.25 (0.09); p = 0.001) was observed. Similarly, values were strongly influenced by variations of the anterior. Additionally, total average keratometry values increased from preoperative 44.05 (2.25) D to 44.6 (1.9) (p = 0.043) 1 month after the surgery. Conclusions: Significant steepening of the anterior cornea and a reduction in both astigmatism and HOA were observed after pterygium excision. The anterior corneal surface was an essential component of the total postoperative corneal topography values. Three-dimensional swept-source AS-OCT imaging seems to be a valuable tool for monitoring both the progression of the disease and postoperative effects in pterygium eyes.

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Section: Discussionmentioning

confidence: 99%

Effect of Pterygium Removal Combined with Conjunctival Autograft on Corneal Parameters in Swept-Source Imaging

Wiącek

Kuśmierz-Wojtasik

Kowalska

et al. 2022

JCM

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“…In our meta-analysis, 23 trials reported the recurrence rate. Of these studies, five [13, 28, 31, 39, 40] reported no recurrence in both groups, which may be related to the short follow-up time. Ratnalingam et al [29] found no significant difference between suture and FG groups at 1 month and 6 months postoperatively.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of fibrin glue versus sutures for attaching conjunctival autografts in pterygium surgery: a systematic review with meta-analysis and trial sequential analysis of evidence

Lan

Xiao

Wang³

et al. 2017

Oncotarget

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Previous meta-analyses have been conducted to compare the efficacy of fibrin glue (FG) versus sutures in pterygium surgery; however, additional clinical trials have since been published. Therefore, we conducted an updated meta-analysis to further explore the association between FG application in pterygium surgery, and the recurrence rate, complication rate, and surgical duration. An electronic literature search for eligible studies published before July 29, 2016 was conducted across multiple databases. Odds ratios (ORs), standardized mean difference (SMD), and 95% confidence intervals (CI) were calculated. Publication bias of the included articles was evaluated by funnel plots. Differences in recurrence rate and complication rate between the FG and suture groups were evaluated in terms of OR with 95% CI, and SMD with 95% CI were used to estimate the difference in surgical duration. Trial sequential analysis (TSA) was used to determine whether the currently available evidence was sufficient and conclusive. Twenty-four studies were included in this study. The pooled ORs for recurrence rate and complication rate were 0.35 and 1.121, respectively. The pooled SMD for surgical duration was −4.142. The TSA results indicated that evidence of the effect was sufficient in the recurrence group and surgical duration group. Although there was no difference in complication rate between FG and sutures, the apparent advantages of FG over sutures are shorter surgical duration and greater reduction in the recurrence rate of pterygium.

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“…11 The use of fibrin glue, instead of suture, significantly reduces the surgery time and increases the patient's comfort postoperatively and prevents suture-related complications. [12][13][14][15][16][17][18] Both these two techniques also reduce recurrence rate, but it is controversial that fibrin glue usage technique decreases the recurrence rate more than the suturing technique. Some authors report that it is more effective in decreasing the recurrence rate.…”

Section: Discussionmentioning

confidence: 99%

The Use of Fibrin Glue in Primary and Recurrent Pterygium Surgery

Çetinkaya¹,

Cetinkaya²,

Gürdağ³

et al. 2016

Turkiye Klinikleri J Ophthalmol

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Vascularization of Conjunctival Autografts in Pterygium Surgery: Comparison of Fibrin Glue with Sutures

Abstract: Fibrin glue fixation of conjunctival autografts led to more vascularization in the early postoperative period than suture fixated grafts, which in turn may have significance in terms of graft health and pterygium recurrence.

Cited by 8 publications

References 27 publications

Effect of Pterygium Removal Combined with Conjunctival Autograft on Corneal Parameters in Swept-Source Imaging

Effect of Pterygium Removal Combined with Conjunctival Autograft on Corneal Parameters in Swept-Source Imaging

Efficacy of fibrin glue versus sutures for attaching conjunctival autografts in pterygium surgery: a systematic review with meta-analysis and trial sequential analysis of evidence

The Use of Fibrin Glue in Primary and Recurrent Pterygium Surgery

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