Vascular smooth muscle mechanics in isolated perfused segments of carotid arteries

Spiral Laminar Flow: a Survey of a Three-Dimensional Arterial Flow Pattern in a Group of Volunteers

“…19e21 The non-planar geometry of parts of the arterial tree is known to induce or propagate spiral laminar flow. 11,22e24 Finally, the arrangement of the muscle and elastin fibres of the arteries has been shown to be helical, 25,26 although whether this is a coincidence or has a more direct relationship with the nature of flow within the vessel is as yet unknown.…”

Changes in the Mechanical and Biochemical Properties of Aortic Tissue due to Cold Storage

“…Arteries are complex structures where the extracellular matrix (ECM) bears the vast majority of wall stress [14]. While the collagen and elastin network is generally responsible for the passive mechanics of the artery, the smooth muscle cells provide the active contraction to facilitate blood flow [15][16][17]. Cold storage can result in bulk redistribution of water, damage to the collagen network from ice crystals, and breaking of cross-links in the ECM [9,[18][19][20][21].…”

Vasodilation promoted by (E,E)-farnesol involving ion channels in human umbilical arteries

“…In general, under in vivo conditions, the vascular tonus is the sum of three components: (1) the basal or resting tonus (myogenic and intrinsic) dependent on stretch (transmural pressure) and flow (shear forces); (2) the tonus induced by agonists; (3) and the matrix elements in the vessel wall [ [24] , [25] , [26] ]. In this sense, experimental evaluations on the basal tone may have some clinical utility, since in the physiopathology of hypertensive disorders in pregnancy, such as preeclampsia, there is a decrease in the activity of the Na + /Ca 2+ exchanger (NCX) in HUA that may be implicated in an abnormal regulation of the basal tone [ 27 , 28 ].…”