Vascular Graft Pre-Treatment with Daptomycin Prior to Implantation Prevents Graft Infection with<i>Staphylococcus aureus</i>in an In Vivo Model

Salmoukas, Christina; Ruemke, Stefan; Rubalskii, Evgenii; Burgwitz, Karin; Haverich, Axel; Kuehn, C.

doi:10.1089/sur.2019.124

Cited by 5 publications

(1 citation statement)

References 28 publications

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“…Of substantial importance in the field of antimicrobial PET are its composites, equipped with antibacterial organic additivities (mainly chitosan and antibiotics [21,22,[41][42][43][44][45][46][47][48][49][50]). Thus, antimicrobial hybrids of PET-organic biocides can be represented by PET-Chitosan [21,22,41], PET-Chitosan/hyaluronic acid [42][43][44], PET-Antibiotics (e.g., rifampin [45]; cephalosporin [46]; gentamicin [47], tetracycline [48]; chlorhexidine [49] or daptomycin [50]).…”

Section: Introductionmentioning

confidence: 99%

Deposition of Copper on Polyester Knitwear Fibers by a Magnetron Sputtering System. Physical Properties and Evaluation of Antimicrobial Response of New Multi-Functional Composite Materials

et al. 2020

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In this study, copper films were deposited by magnetron sputtering on poly(ethylene terephthalate) knitted textile to fabricate multi-functional, antimicrobial composite material. The modified knitted textile composites were subjected to microbial activity tests against colonies of Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria and antifungal tests against Chaetomium globosum fungal molds species. The prepared samples were characterized by UV/VIS transmittance, scanning electron microscopy (SEM), tensile and filtration parameters and the ability to block UV radiation. The performed works proved the possibility of manufacturing a new generation of antimicrobial textile composites with barrier properties against UV radiation, produced by a simple, zero-waste method. The specific advantages of using new poly(ethylene terephthalate)-copper composites are in biomedical applications areas.

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Section: Introductionmentioning

confidence: 99%

Deposition of Copper on Polyester Knitwear Fibers by a Magnetron Sputtering System. Physical Properties and Evaluation of Antimicrobial Response of New Multi-Functional Composite Materials

et al. 2020

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Artificial Neutrophils Against Vascular Graft Infection

Jiang,

Xu,

Gao

et al. 2024

Advanced Science

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Efficient neutrophil migration to infection sites plays a vital role in the body's defense against bacterial infections and natural immune responses. Neutrophils have a short lifespan and cannot be mass‐cultured in vitro. Therefore, developing more stable artificial neutrophils (AN) in a controllable manner has become a research focus. However, existing AN lack chemotaxis, which is the ability to migrate toward high‐signal‐concentration positions in a dynamic blood‐ flow environment. Supplying AN with chemotaxis is key to designing AN that are more similar to natural neutrophils in terms of morphology and function. In this study, micrometer‐sized, spherical, biocompatible AN are developed. These AN consist of zeolitic imidazolate framework‐8 nanoparticles encapsulating two enzymes, coacervate droplet frameworks, and outer phospholipid bilayers carrying enzymes. The AN exhibit responsiveness to elevated hydrogen peroxide levels at inflammation sites, actively chemotaxing toward these sites along concentration gradients. They also demonstrate effective combat against Staphylococcus aureus infections. The capabilities of the AN are further validated through in vitro experiments and in vivo evaluations using vascular graft infection models. This study replicates natural neutrophils in terms of chemical composition, functionality, and physiological impact. It introduces new ideas for advancing the development of advanced artificial cells.

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Cobalt loaded electrospun poly(ε-caprolactone) grafts promote antibacterial activity and vascular regeneration in a diabetic rat model

et al. 2022

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Vascular Graft Pre-Treatment with Daptomycin Prior to Implantation Prevents Graft Infection withStaphylococcus aureusin an In Vivo Model

Cited by 5 publications

References 28 publications

Deposition of Copper on Polyester Knitwear Fibers by a Magnetron Sputtering System. Physical Properties and Evaluation of Antimicrobial Response of New Multi-Functional Composite Materials

Deposition of Copper on Polyester Knitwear Fibers by a Magnetron Sputtering System. Physical Properties and Evaluation of Antimicrobial Response of New Multi-Functional Composite Materials

Artificial Neutrophils Against Vascular Graft Infection

Cobalt loaded electrospun poly(ε-caprolactone) grafts promote antibacterial activity and vascular regeneration in a diabetic rat model

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