Vascular Graft Infection Imaging

Infection of Vascular Prostheses: A Comprehensive Review

“…Also, it detects radiolabeled leukocyte uptake by white blood cell (WBC) scintigraphy based on the capacity of a radiolabeled granulocyte to reach the infection site and to accumulate in infectious tissues. WBC scintigraphy together with single-photon emission computed tomography (SPECT/CT) seems to increase diagnostic power [21,[84][85][86][87][88][89][90][91][92][93][94][95][96][97][98][99][100][101][102][103].…”

“…The graft is anchored in place by a balloon-expandable or self-expanding metal frame that supports all or part of the graft and provides a tight seal proximal and distal to the diseased segment of the artery. Since it circumvents the need for laparotomy, the crossclamping of the artery, and the obligatory blood loss associated with the opening of the aneurysm sac, the technique has been shown to reduce the morbidity and mortality associated with conventional surgery, and it expands the patient pool to include patients with severe medical-and co-morbidities who were previously denied treatment [11][12][13][14][15][16][17][18][19][20][21][22]. According to the location of implantation, grafts may be extra-cavitary (groins and lower limbs) and intra-cavitary (abdominal or thoracic aorta) [21,22].…”

“…Since it circumvents the need for laparotomy, the crossclamping of the artery, and the obligatory blood loss associated with the opening of the aneurysm sac, the technique has been shown to reduce the morbidity and mortality associated with conventional surgery, and it expands the patient pool to include patients with severe medical-and co-morbidities who were previously denied treatment [11][12][13][14][15][16][17][18][19][20][21][22]. According to the location of implantation, grafts may be extra-cavitary (groins and lower limbs) and intra-cavitary (abdominal or thoracic aorta) [21,22].…”

“…VGEIs are managed mainly through surgical removal, revascularization, and long-term antibiotic treatment. The explantation of an infected graft may determine important mortality rates (18-30%), while conservative According to the location of implantation, grafts may be extra-cavitary (groins and lower limbs) and intra-cavitary (abdominal or thoracic aorta) [21,22].…”

“…VGEIs are managed mainly through surgical removal, revascularization, and long-term antibiotic treatment. The explantation of an infected graft may determine important mortality rates (18-30%), while conservative management with long-term antibiotic therapy may result in a very high mortality rate, reaching about 100%, if the VGEI is not completely resolved [21].…”